COPT1
label: CTR1
label: SLC31A1
label: UniProt:O15431 SLC31A1

LSH
label: NRAMP
label: NRAMP1
label: SLC11A1
label: UniProt:P49279 SLC11A1

DCT1
label: DMT1
label: NRAMP2
label: OK/SW-cl.20
label: SLC11A2
label: UniProt:P49281 SLC11A2

SLC30A6
label: UniProt:Q6NXT4 SLC30A6
label: ZNT6

SLC39A5
label: UniProt:Q6ZMH5 SLC39A5
label: ZIP5

SLC30A8
label: UniProt:Q8IWU4 SLC30A8
label: ZNT8

SLC30A7
label: UniProt:Q8NEW0 SLC30A7
label: ZNT7
label: ZNTL2

SLC30A5
label: UNQ863/PRO1879
label: UniProt:Q8TAD4 SLC30A5
label: ZNT5
label: ZNTL1
label: ZTL1

HKE4
label: RING5
label: SLC39A7
label: UniProt:Q92504 SLC39A7

SLC30A3
label: UniProt:Q99726 SLC30A3
label: ZNT3

SLC30A2
label: UniProt:Q9BRI3 SLC30A2
label: ZNT2

BIGM103
label: PP3105
label: SLC39A8
label: UniProt:Q9C0K1 SLC39A8
label: ZIP8

KIAA1265
label: SLC39A10
label: UniProt:Q9ULF5 SLC39A10
label: ZIP10

SLC30A1
label: UniProt:Q9Y6M5 SLC30A1
label: ZNT1

NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages
type: Restriction
  on property: BFO_0000066
  some values from: GO_0031902
type: Restriction
  on property: enabled by
  some values from: LSH
type: GO_0051139
BFO_0000050: Metal ion SLC transporters

DCT1 (NRAMP2) mediates divalent iron uptake across the apical membrane of enterocytes
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: DCT1
type: GO_0005381
BFO_0000050: Metal ion SLC transporters
directly activates: Ferroportin mediates iron influx across the basolateral membrane of enterocytes
directly activates: Ferroportin mediates iron efflux on macrophages
directly activates: Catalysis662
directly activates: Catalysis663

Ferroportin mediates iron influx across the basolateral membrane of enterocytes
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005381
BFO_0000050: Metal ion SLC transporters
directly activates: BiochemicalReaction1783
directly activates: Catalysis759

Ferroportin mediates iron efflux on macrophages
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005381
BFO_0000050: Metal ion SLC transporters
directly activates: BiochemicalReaction1782
directly activates: Catalysis758

ZnT1 mediates the efflux of zinc from the cell
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: SLC30A1
type: Restriction
  on property: enabled by
  some values from: SLC30A1
type: Restriction
  on property: enabled by
  some values from: SLC30A1
type: Restriction
  on property: enabled by
  some values from: SLC30A1
type: GO_0005385
BFO_0000050: Zinc efflux and compartmentalization by the SLC30 family

ZnT2 facilitates zinc vesicular sequestration
type: Restriction
  on property: BFO_0000066
  some values from: GO_0010008
type: Restriction
  on property: BFO_0000066
  some values from: GO_0010008
type: Restriction
  on property: BFO_0000066
  some values from: GO_0010008
type: Restriction
  on property: BFO_0000066
  some values from: GO_0010008
type: Restriction
  on property: enabled by
  some values from: SLC30A2
type: Restriction
  on property: enabled by
  some values from: SLC30A2
type: Restriction
  on property: enabled by
  some values from: SLC30A2
type: Restriction
  on property: enabled by
  some values from: SLC30A2
type: GO_0005385
BFO_0000050: Zinc efflux and compartmentalization by the SLC30 family

ZnT3 transports zinc into synaptic vesicles
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030672
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030672
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030672
type: Restriction
  on property: enabled by
  some values from: SLC30A3
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030672
type: Restriction
  on property: enabled by
  some values from: SLC30A3
type: Restriction
  on property: enabled by
  some values from: SLC30A3
type: Restriction
  on property: enabled by
  some values from: SLC30A3
type: GO_0005385
BFO_0000050: Zinc efflux and compartmentalization by the SLC30 family

ZnT5 transports zinc into secretory granules in pancreatic beta cells
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030667
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030667
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030667
type: Restriction
  on property: enabled by
  some values from: SLC30A5
type: Restriction
  on property: enabled by
  some values from: SLC30A5
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030667
type: Restriction
  on property: enabled by
  some values from: SLC30A5
type: Restriction
  on property: enabled by
  some values from: SLC30A5
type: GO_0005385
BFO_0000050: Zinc efflux and compartmentalization by the SLC30 family

ZnT6 transports zinc into the golgi apparatus
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: SLC30A6
type: Restriction
  on property: enabled by
  some values from: SLC30A6
type: Restriction
  on property: enabled by
  some values from: SLC30A6
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: SLC30A6
type: GO_0005385
BFO_0000050: Zinc efflux and compartmentalization by the SLC30 family

ZnT7 transports zinc into the golgi apparatus
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: SLC30A7
type: Restriction
  on property: enabled by
  some values from: SLC30A7
type: Restriction
  on property: enabled by
  some values from: SLC30A7
type: Restriction
  on property: enabled by
  some values from: SLC30A7
type: GO_0005385
BFO_0000050: Zinc efflux and compartmentalization by the SLC30 family

ZnT8 transports zinc into the secretory vesicles of pancreatic beta cells specifically
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030667
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030667
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030667
type: Restriction
  on property: BFO_0000066
  some values from: GO_0030667
type: Restriction
  on property: enabled by
  some values from: SLC30A8
type: Restriction
  on property: enabled by
  some values from: SLC30A8
type: Restriction
  on property: enabled by
  some values from: SLC30A8
type: Restriction
  on property: enabled by
  some values from: SLC30A8
type: GO_0005385
BFO_0000050: Zinc efflux and compartmentalization by the SLC30 family

hZIP1-4 mediate zinc uptake by cells
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005385
BFO_0000050: Zinc influx into cells by the SLC39 gene family

hZIP5 mediates zinc uptake by cells
type: Restriction
  on property: enabled by
  some values from: SLC39A5
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: SLC39A5
type: Restriction
  on property: enabled by
  some values from: SLC39A5
type: Restriction
  on property: enabled by
  some values from: SLC39A5
type: GO_0005385
BFO_0000050: Zinc influx into cells by the SLC39 gene family

ZIP6 and ZIP14 mediate zinc influx into cells
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005385
BFO_0000050: Zinc influx into cells by the SLC39 gene family

ZIP7 mediates zinc efflux from the endoplasmic reticulum
type: Restriction
  on property: enabled by
  some values from: HKE4
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: HKE4
type: Restriction
  on property: enabled by
  some values from: HKE4
type: Restriction
  on property: enabled by
  some values from: HKE4
type: GO_0005385
BFO_0000050: Zinc influx into cells by the SLC39 gene family

ZIP8 mediates zinc influx into cells
type: Restriction
  on property: enabled by
  some values from: BIGM103
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: BIGM103
type: Restriction
  on property: enabled by
  some values from: BIGM103
type: Restriction
  on property: enabled by
  some values from: BIGM103
type: GO_0005385
BFO_0000050: Zinc influx into cells by the SLC39 gene family

hZIP10 mediates zinc influx into cells
type: Restriction
  on property: enabled by
  some values from: KIAA1265
type: Restriction
  on property: enabled by
  some values from: KIAA1265
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: KIAA1265
type: Restriction
  on property: enabled by
  some values from: KIAA1265
type: GO_0005385
BFO_0000050: Zinc influx into cells by the SLC39 gene family

Cellular copper transport is mediated by human copper transporter 1 hCTR1
type: Restriction
  on property: enabled by
  some values from: COPT1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0005375
BFO_0000050: Metal ion SLC transporters

MagT transporters mediate magnesium uptake into cells
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0015095
BFO_0000050: Metal ion SLC transporters

Metal ion SLC transporters
type: GO_0008150

Zinc transporters
type: GO_0008150
BFO_0000050: Metal ion SLC transporters

Zinc efflux and compartmentalization by the SLC30 family
type: GO_0008150
BFO_0000050: Zinc transporters

Zinc influx into cells by the SLC39 gene family
type: GO_0008150
BFO_0000050: Zinc transporters