Phosphorylation of TBSMs in LAT
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004713
BFO_0000050: Generation of second messenger molecules
directly activates: Recruitment of Gads to LAT
directly activates: Recruitment of PLC-gamma1 to LAT

Recruitment of Gads to LAT
type: GO_0003674
BFO_0000050: Generation of second messenger molecules
directly activates: Recruitment of SLP-76 to Gads

Recruitment of SLP-76 to Gads
type: GO_0003674
BFO_0000050: Generation of second messenger molecules
directly activates: Phosphorylation of SLP-76
directly activates: Catalysis233

Phosphorylation of SLP-76
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004713
BFO_0000050: Generation of second messenger molecules
directly activates: Recruitment of ITK to SLP-76
directly activates: Recruitment of PLC-gamma1 to SLP-76
directly activates: p-SLP-76 binds ADAP

Recruitment of ITK to SLP-76
type: GO_0003674
BFO_0000050: Generation of second messenger molecules
directly activates: Phosphorylation of PLC-gamma1
directly activates: Catalysis234

Recruitment of PLC-gamma1 to SLP-76
type: GO_0003674
BFO_0000050: Generation of second messenger molecules
directly activates: Phosphorylation of PLC-gamma1
directly activates: Catalysis234

Recruitment of PLC-gamma1 to LAT
type: GO_0003674
BFO_0000050: Generation of second messenger molecules
directly activates: Phosphorylation of PLC-gamma1
directly activates: Catalysis234

Phosphorylation of PLC-gamma1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004713
BFO_0000050: Generation of second messenger molecules
directly activates: Disassociation of PLC-gamma1 from LAT
directly activates: Disassociation of PLC-gamma1 from SLP-76
directly activates: Translocation of PLC-gamma1 to PIP2

Disassociation of PLC-gamma1 from LAT
type: GO_0003674
BFO_0000050: Generation of second messenger molecules
directly activates: Translocation of PLC-gamma1 to PIP2

Disassociation of PLC-gamma1 from SLP-76
type: GO_0003674
BFO_0000050: Generation of second messenger molecules
directly activates: Translocation of PLC-gamma1 to PIP2

Translocation of PLC-gamma1 to PIP2
type: GO_0003674
BFO_0000050: Generation of second messenger molecules
directly activates: PLC-gamma1 hydrolyses PIP2
directly activates: Catalysis235

PLC-gamma1 hydrolyses PIP2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004435
BFO_0000050: Generation of second messenger molecules
directly activates: BiochemicalReaction652

p-SLP-76 binds ADAP
type: GO_0003674
BFO_0000050: Generation of second messenger molecules

p-SLP-76:ADAP binds Ena/VASP
type: GO_0003674
BFO_0000050: Generation of second messenger molecules

p-SLP-76 binds NCK
type: GO_0003674
BFO_0000050: Generation of second messenger molecules

NCK binds PAK
type: GO_0003674
BFO_0000050: Generation of second messenger molecules

NCK recruits WASP
type: GO_0003674
BFO_0000050: Generation of second messenger molecules
directly activates: BiochemicalReaction1226

Generation of second messenger molecules
type: GO_0008150