G alpha (i) inhibits adenylate cyclase
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi
Liganded Gi-activating GPCR acts as a GEF for Gi
The Ligand:GPCR:Gi complex dissociates
Opsins that act as GEFs for G alpha-t
G alpha (i) auto-inactivates by hydrolysing GTP to GDP
Inactive G alpha (i) reassociates with G beta:gamma
G alpha (i) signalling events