FUR
label: FURIN
label: PACE
label: PCSK3
label: UniProt:P09958 FURIN

Fibrillin C-terminal processing
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: FUR
type: GO_0004252
BFO_0000050: Elastic fibre formation
directly activates: Fibrillin-1 binds integrins
directly activates: Fibrillin microfibril assembly

Fibrillin-1 binds integrins
type: GO_0003674
BFO_0000050: Elastic fibre formation

Fibrillin microfibril assembly
type: GO_0003674
BFO_0000050: Elastic fibre formation
directly activates: MFAP2, MFAP5 bind microfibrils
directly activates: Tropoelastin associates with microfibrils
directly activates: Elastic fibres bind associated proteins

MFAP2, MFAP5 bind microfibrils
type: GO_0003674
BFO_0000050: Elastic fibre formation

Tropoelastin forms aggregate globules
type: GO_0003674
BFO_0000050: Elastic fibre formation
directly activates: Tropoelastin associates with microfibrils

Tropoelastin associates with microfibrils
type: GO_0003674
BFO_0000050: Elastic fibre formation
directly activates: Elastin cross-linking by lysyl oxidase
directly activates: Catalysis943

Elastin cross-linking by lysyl oxidase
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005576
type: GO_0004720
BFO_0000050: Elastic fibre formation

FBLN1, FBLN2 bind fibronectin
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres
label: Fibulin-1 and -2 bind fibronectin

Fibulin binds elastic fibres
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres

Emilin is found in elastic fibres
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres

LTBP1, LTBP3 bind TGF-Beta
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres

LTBP4 binds TGF-Beta-1
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres

Latent TGF-beta-1 binds integrins
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres

Latent TGF-beta-3 binds integrins
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres

Fibrillins bind BMPs
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres

Fibrillin-1 binds latent TGF-beta
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres

Elastic fibres bind associated proteins
type: GO_0003674
BFO_0000050: Molecules associated with elastic fibres

Elastic fibre formation
type: GO_0008150

Molecules associated with elastic fibres
type: GO_0008150
BFO_0000050: Elastic fibre formation