CYP5
label: CYP5A1
label: TBXAS1
label: UniProt:P24557 TBXAS1

PGH2 is isomerised to PGI2 by PTGIS
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0008116
BFO_0000050: Eicosanoids
directly activates: BiochemicalReaction5216
label: Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2

PGH2 is isomerised to TXA2 by TBXAS1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: Restriction
  on property: enabled by
  some values from: CYP5
type: GO_0004796
BFO_0000050: Eicosanoids
directly activates: BiochemicalReaction5218
label: Thromboxane synthase (CYP5A1) mediates the isomerization of prostaglandin H2 to thromboxane A2

CYP4F2 omega-hydroxylates leukotriene B4, thus inactivating it
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0050051
BFO_0000050: Eicosanoids
directly activates: BiochemicalReaction5227
directly activates: Catalysis2477
label: LTB4 is hydroxylated to 20oh-LTB4 by CYP4F2/4F3

CYP4F8 hydroxylates prostaglandin H2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005789
type: GO_0019825
BFO_0000050: Eicosanoids

Eicosanoids
type: GO_0008150