ACSM2
ACSM2B
HYST1046
UniProt:Q68CK6 ACSM2B
ACGNAT
CAT
GAT
GLYAT
UniProt:Q6IB77 GLYAT
Benzoate and Coenzyme A react to form benzoyl-CoA thioester
benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate
Benzoyl-CoA forms an amide bond with glycine
benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A
Synthesis of phenylacetyl CoA from phenylacetate and Coenzyme A
phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate
Synthesis of phenylacetyl glutamine from phenylacetyl-CoA and glutamine
phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A
Salicylic acid and Coenzyme A react to form salicylate-CoA thioester
salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate
Salicylate-CoA forms an amide bond with glycine
salicylate-CoA + glycine => salicyluric acid + Coenzyme A
Conjugation of carboxylic acids
Conjugation of benzoate with glycine
Conjugation of phenylacetate with glutamine
Conjugation of salicylate with glycine