COMT
UniProt:P21964 COMT
DAT1
SLC6A3
UniProt:Q01959 SLC6A3
Reuptake of dopamine from the synaptic celft into neurons
Reuptake of dopamine from the synaptic cleft into neurons
methylation of Dopamine to form 3-Methoxytyramine
Oxidation of 3-Methoxytyramine to homovanillic acid
oxidation of dopamine to 3,4dihydroxyphenylacetic acid (DOPAC)
Methylation of 3,4-dihydroxyphenylacetic acid to homovanillic acid
Clearance of dopamine
Dopamine clearance from the synaptic cleft
Enzymatic degradation of dopamine by COMT
Enzymatic degradation of Dopamine by monoamine oxidase