FYN
label: UniProt:P06241 FYN

Interaction of DAP12 and SIRP beta
type: GO_0003674
BFO_0000050: Signal regulatory protein (SIRP) family interactions

Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin
type: GO_0003674
BFO_0000050: Adherens junctions interactions

Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin
type: GO_0003674
BFO_0000050: Adherens junctions interactions

Interaction of Afadin with F-actin
type: GO_0003674
BFO_0000050: Adherens junctions interactions

Interaction of Nectins with Afadin
type: GO_0003674
BFO_0000050: Adherens junctions interactions

Cis-homodimerization of nectins
type: GO_0003674
BFO_0000050: Adherens junctions interactions

Transhomodimerization of Nectins
type: GO_0003674
BFO_0000050: Adherens junctions interactions

Transhomodimerization of Nectin-like (Necl) proteins
type: GO_0003674
BFO_0000050: Adherens junctions interactions

Nectin-1:PVRL3 trans heterodimer formation
type: GO_0003674
BFO_0000050: Nectin/Necl trans heterodimerization

Nectin-1:Nectin-4 trans heterodimer formation
type: GO_0003674
BFO_0000050: Nectin/Necl trans heterodimerization

Nectin-2:Nectin 3 trans heterodimer interaction
type: GO_0003674
BFO_0000050: Nectin/Necl trans heterodimerization

Necl-1:Nectin-1 trans heterodimer interaction
type: GO_0003674
BFO_0000050: Nectin/Necl trans heterodimerization

Necl-1:Nectin 3 trans heterodimer interaction
type: GO_0003674
BFO_0000050: Nectin/Necl trans heterodimerization

Necl-1:Necl-2 trans heterodimer interaction
type: GO_0003674
BFO_0000050: Nectin/Necl trans heterodimerization

Necl-2:Nectin 3 trans heterodimer interaction
type: GO_0003674
BFO_0000050: Nectin/Necl trans heterodimerization

PVR:PVRL3 trans heterodimer interaction
type: GO_0003674
BFO_0000050: Nectin/Necl trans heterodimerization

Claudins create paired strands through homophilic and heterophilic cis and trans interactions
type: GO_0003674
BFO_0000050: Tight junction interactions

Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions
type: GO_0003674
BFO_0000050: Tight junction interactions

Crumbs forms a ternary complex with Pals1 and PATJ at tight junctions
type: GO_0003674
BFO_0000050: Tight junction interactions

Formation of the PINCH-ILK-parvin complex
type: GO_0003674
BFO_0000050: Cell-extracellular matrix interactions
directly activates: Localization of the PINCH-ILK-PARVIN complex to focal adhesions

ILK interacts with beta-1 integrin
type: GO_0003674
BFO_0000050: Localization of the PINCH-ILK-PARVIN complex to focal adhesions

PARVA associates with Paxillin
type: GO_0003674
BFO_0000050: Localization of the PINCH-ILK-PARVIN complex to focal adhesions
BFO_0000050: Regulation of cytoskeletal remodeling and cell spreading by IPP complex components

PARVB/Affixin interacts with alpha PIX
type: GO_0003674
BFO_0000050: Regulation of cytoskeletal remodeling and cell spreading by IPP complex components

Rsu-1 interacts with Pinch1
type: GO_0003674
BFO_0000050: Regulation of cytoskeletal remodeling and cell spreading by IPP complex components

Association of PARVA with TESK1
type: GO_0003674
BFO_0000050: Regulation of cytoskeletal remodeling and cell spreading by IPP complex components

PARVB interacts with Alpha-actinin
type: GO_0003674
BFO_0000050: Regulation of cytoskeletal remodeling and cell spreading by IPP complex components

Mig-2 recruits Migfilin to the cell-ECM adhesions
type: GO_0003674
BFO_0000050: Cell-extracellular matrix interactions

MigFilin associates with Filamin and F-actin
type: GO_0003674
BFO_0000050: Cell-extracellular matrix interactions

Migfilin interacts with VASP
type: GO_0003674
BFO_0000050: Cell-extracellular matrix interactions

Interaction of Plectin with Integrin beta 4
type: GO_0003674
BFO_0000050: Type I hemidesmosome assembly

BP180 interacts intracellularly with plectin and integrin beta4
type: GO_0003674
BFO_0000050: Type I hemidesmosome assembly

BP180 interacts extracellularly with Laminin 332
type: GO_0003674
BFO_0000050: Type I hemidesmosome assembly

BP230 is recruited to the hemidesmosome
type: GO_0003674
BFO_0000050: Type I hemidesmosome assembly

BP230 interacts with keretin K5/K14
type: GO_0003674
BFO_0000050: Type I hemidesmosome assembly

CD151 interacts with BP180 and the integrin alpha 6 subunit
type: GO_0003674
BFO_0000050: Type I hemidesmosome assembly

SIRP alpha binds CD47
type: GO_0003674
BFO_0000050: Signal regulatory protein (SIRP) family interactions
directly activates: Phosphorylation of ITIM in SIRP alpha
directly activates: Catalysis1441

Phosphorylation of ITIM in SIRP alpha
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004713
BFO_0000050: Signal regulatory protein (SIRP) family interactions
directly activates: Recruitment of SHP-2 and SHP-1 to pSIRP alpha
directly activates: Recruitment of SCAP2 to pSIRP alpha
directly activates: Recruitment of FYB to pSIRP alpha
directly activates: Recruitment of PYK2 to pSIRP alpha
directly activates: Recruitment of Grb2 to pSIRP alpha

Recruitment of SHP-2 and SHP-1 to pSIRP alpha
type: GO_0003674
BFO_0000050: Signal regulatory protein (SIRP) family interactions

Recruitment of SCAP2 to pSIRP alpha
type: GO_0003674
BFO_0000050: Signal regulatory protein (SIRP) family interactions

Recruitment of FYB to pSIRP alpha
type: GO_0003674
BFO_0000050: Signal regulatory protein (SIRP) family interactions

Recruitment of PYK2 to pSIRP alpha
type: GO_0003674
BFO_0000050: Signal regulatory protein (SIRP) family interactions

Recruitment of Grb2 to pSIRP alpha
type: GO_0003674
BFO_0000050: Signal regulatory protein (SIRP) family interactions

SP-A/SP-D binds SIRP alpha
type: GO_0003674
BFO_0000050: Signal regulatory protein (SIRP) family interactions

SIRP gamma binds CD47
type: GO_0003674
BFO_0000050: Signal regulatory protein (SIRP) family interactions

DSCAM/DSCAML1 homodimerization
type: GO_0003674
BFO_0000050: DSCAM interactions

DSCAM binds DCC
type: GO_0003674
BFO_0000050: DSCAM interactions

DSCAM binds Netrin-1
type: GO_0003674
BFO_0000050: DSCAM interactions

DSCAM associates with Rac1-GTP:pPAK1
type: GO_0003674
BFO_0000050: DSCAM interactions

Activation of JNK by DSCAM
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004674
BFO_0000050: DSCAM interactions

Activation of p38MAPK by DSCAM
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004707
BFO_0000050: DSCAM interactions

Nephrin trans-homophilic interaction
type: GO_0003674
BFO_0000050: Nephrin interactions
directly activates: Cis-Heterodimerization of nephrin and NEPH1
directly activates: Heterodimerization of nephrin and NEPH2/NEPH3

Cis-Heterodimerization of nephrin and NEPH1
type: GO_0003674
BFO_0000050: Nephrin interactions
directly activates: Phosphorylation of nephrin by the Src family kinase Fyn
directly activates: Nephrin binds CASK
directly activates: Interaction of IQGAP1 with nephrin
directly activates: Interaction of nephrin with adherens junction-associated proteins
directly activates: Catalysis1444

Heterodimerization of nephrin and NEPH2/NEPH3
type: GO_0003674
BFO_0000050: Nephrin interactions

Phosphorylation of nephrin by the Src family kinase Fyn
type: Restriction
  on property: enabled by
  some values from: FYN
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: FYN
type: GO_0004713
BFO_0000050: Nephrin interactions
directly activates: Nephrin binds NCK
directly activates: Nephrin interacts with Podocin
directly activates: Nephrin binds CD2AP
directly activates: p85 associates with both p-Nephrin and CD2AP

Nephrin binds NCK
type: GO_0003674
BFO_0000050: Nephrin interactions
directly activates: Nephrin mediated activation of N-WASP

Nephrin mediated activation of N-WASP
type: GO_0003674
BFO_0000050: Nephrin interactions

Nephrin interacts with Podocin
type: GO_0003674
BFO_0000050: Nephrin interactions

Nephrin binds CD2AP
type: GO_0003674
BFO_0000050: Nephrin interactions

p85 associates with both p-Nephrin and CD2AP
type: GO_0003674
BFO_0000050: Nephrin interactions

Nephrin binds CASK
type: GO_0003674
BFO_0000050: Nephrin interactions

Interaction of IQGAP1 with nephrin
type: GO_0003674
BFO_0000050: Nephrin interactions

Interaction of nephrin with adherens junction-associated proteins
type: GO_0003674
BFO_0000050: Nephrin interactions

Cell-Cell communication
type: GO_0008150

Cell junction organization
type: GO_0008150
BFO_0000050: Cell-Cell communication

Cell-cell junction organization
type: GO_0008150
BFO_0000050: Cell junction organization

Adherens junctions interactions
type: GO_0008150
BFO_0000050: Cell-cell junction organization

Nectin/Necl trans heterodimerization
type: GO_0008150
BFO_0000050: Adherens junctions interactions

Tight junction interactions
type: GO_0008150
BFO_0000050: Cell-cell junction organization

Cell-extracellular matrix interactions
type: GO_0008150
BFO_0000050: Cell junction organization

Localization of the PINCH-ILK-PARVIN complex to focal adhesions
type: GO_0008150
BFO_0000050: Cell-extracellular matrix interactions

Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
type: GO_0008150
BFO_0000050: Cell-extracellular matrix interactions

Type I hemidesmosome assembly
type: GO_0008150
BFO_0000050: Cell junction organization

Signal regulatory protein (SIRP) family interactions
type: GO_0008150
BFO_0000050: Cell-Cell communication

DSCAM interactions
type: GO_0008150
BFO_0000050: Cell-Cell communication

Nephrin interactions
type: GO_0008150
BFO_0000050: Cell-Cell communication