Gene Ontology Ontology Comparison Report ========================== Files used: - file 1 (old): go-2011-10-01.obo; date: 30:09:2011 14:21; CVS revision: 1.2291 - file 2 (new): go-2011-10-08.obo; date: 07:10:2011 17:16; CVS revision: 1.2307 NEW TERMS ========= ID name namespace GO:0002197 xanthine dehydrogenase complex cellular_component GO:0036009 protein-glutamine N-methyltransferase activity molecular_function GO:0036010 protein localization in endosome biological_process GO:0036011 imaginal disc-derived leg segmentation biological_process GO:0052759 coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity molecular_function GO:0052760 coenzyme F420-dependent 2,4-dinitrophenol reductase activity molecular_function GO:0052761 exo-1,4-beta-D-glucosaminidase activity molecular_function GO:0052762 gellan lyase activity molecular_function GO:0052763 ulvan lyase activity molecular_function GO:0052764 exo-oligoalginate lyase activity molecular_function GO:0052765 reduced coenzyme F420 oxidase activity molecular_function GO:0052766 mannoside alpha-1,4-mannosidase activity molecular_function GO:0052767 mannosyl-oligosaccharide 1,6-alpha-mannosidase activity molecular_function GO:0052768 mannosyl-oligosaccharide 1,3-alpha-mannosidase activity molecular_function GO:0052769 beta-6-sulfate-N-acetylglucosaminidase activity molecular_function GO:0052770 coenzyme F390-A hydrolase activity molecular_function GO:0052771 coenzyme F390-G hydrolase activity molecular_function GO:0052772 brefeldin A esterase activity molecular_function GO:0052773 diacetylchitobiose deacetylase activity molecular_function GO:0052774 glucosyl-N-acetylglucosamine glucosaminidase activity molecular_function GO:0052775 endo-1,3-alpha-L-rhamnosidase activity molecular_function GO:0052776 diacetylchitobiose catabolic process to glucosamine and acetate biological_process GO:0052777 diacetylchitobiose catabolic process biological_process GO:0052778 diacetylchitobiose metabolic process biological_process GO:0052779 amino disaccharide metabolic process biological_process GO:0052780 chitobiose metabolic process biological_process GO:0052781 chitobiose catabolic process biological_process GO:0052782 amino disaccharide catabolic process biological_process GO:0052783 reuteran metabolic process biological_process GO:0052784 reuteran biosynthetic process biological_process GO:0052785 cellulose catabolism by endo-processive cellulases biological_process GO:0052786 alpha-linked polysaccharide catabolism to maltotriose biological_process GO:0052787 alpha-linked polysaccharide catabolism to maltopentaose biological_process GO:0052788 d-4,5 unsaturated beta-glucuronyl hydrolase activity molecular_function GO:0052789 mannan 1,3-beta-mannosidase activity molecular_function GO:0052790 chitooligosaccharide deacetylase activity molecular_function GO:0052791 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity molecular_function GO:0052792 endo-xylogalacturonan hydrolase activity molecular_function GO:0052793 pectin acetylesterase activity molecular_function GO:0052794 exo-alpha-(2,3)-sialidase activity molecular_function GO:0052795 exo-alpha-(2,6)-sialidase activity molecular_function GO:0052796 exo-alpha-(2,8)-sialidase activity molecular_function GO:0052797 4-O-methyl-glucuronoyl methylesterase activity molecular_function GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity molecular_function GO:0052799 coenzyme F420-dependent bicyclic nitroimidazole catabolic process molecular_function GO:0052800 bicyclic nitroimidazole catabolic process molecular_function GO:0052801 bicyclic nitroimidazole metabolic process molecular_function GO:0052802 nitroimidazole metabolic process molecular_function GO:0052803 imidazole metabolic process molecular_function GO:0052804 nitroimidazole catabolic process molecular_function GO:0052805 imidazole catabolic process molecular_function GO:0052806 sulfite reductase (coenzyme F420) activity molecular_function GO:0052807 aflatoxin reductase (coenzyme F420) activity molecular_function GO:0052808 reduced coenzyme F420:NADP+ oxidoreductase activity molecular_function GO:0052809 acharan sulfate lyase activity molecular_function GO:0090415 7-hydroxymethyl chlorophyll a reductase activity molecular_function GO:0097169 AIM2 inflammasome complex cellular_component GO:0097170 ADP-L-glycero-beta-D-manno-heptose metabolic process biological_process GO:0097171 ADP-L-glycero-beta-D-manno-heptose biosynthetic process biological_process GO:0097172 N-acetylmuramic acid metabolic process biological_process GO:0097173 N-acetylmuramic acid catabolic process biological_process GO:0097174 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process biological_process GO:0097175 1,6-anhydro-N-acetyl-beta-muramic acid catabolic process biological_process GO:2001109 regulation of lens epithelial cell proliferation biological_process GO:2001110 negative regulation of lens epithelial cell proliferation biological_process GO:2001111 positive regulation of lens epithelial cell proliferation biological_process GO:2001112 regulation of cellular response to hepatocyte growth factor stimulus biological_process GO:2001113 negative regulation of cellular response to hepatocyte growth factor stimulus biological_process GO:2001114 positive regulation of cellular response to hepatocyte growth factor stimulus biological_process OBSOLETIONS =========== GO:0033747, versatile peroxidase activity (molecular_function) Replaced by: GO:0004601 Consider: GO:0052750 GO:0035980, invasive growth in response to nitrogen limitation (biological_process) This term was made obsolete because the GO term 'pseudohyphal growth ; GO:0007124' describes growth under nitrogen-limiting conditions. Consider: GO:0007124 TERM MERGES =========== None TERM CHANGES ============ GO:0002061 : pyrimidine base binding - synonym: "pyrimidine base binding" EXACT [CHEBI:26432] + synonym: "pyrimidine nucleobase binding" EXACT [CHEBI:26432] GO:0002189 : ribose phosphate diphosphokinase complex - synonym: "ribose phosphate diphosphokinase complex" EXACT [] + synonym: "PRPP synthetase complex" EXACT [PMID:9348095] + synonym: "phosphoribosylpyrophosphate synthetase complex" EXACT [PMID:9348095] GO:0003836 : beta-galactoside (CMP) alpha-2,3-sialyltransferase activity - name: beta-galactoside alpha-2,3-sialyltransferase activity + name: beta-galactoside (CMP) alpha-2,3-sialyltransferase activity GO:0004559 : alpha-mannosidase activity - synonym: "p-nitrophenyl-alpha-mannosidase activity" EXACT [EC:3.2.1.24] - synonym: "1,2-alpha-D-mannosidase activity" EXACT [EC:3.2.1.24] - synonym: "1,2-alpha-mannosidase" BROAD [EC:3.2.1.24] + synonym: "p-nitrophenyl-alpha-mannosidase activity" NARROW [EC:3.2.1.24] + synonym: "1,2-alpha-mannosidase" NARROW [EC:3.2.1.24] + synonym: "1,2-alpha-D-mannosidase activity" NARROW [EC:3.2.1.24] GO:0005041 : low-density lipoprotein receptor activity - synonym: "low-density lipoprotein receptor activity" EXACT [GOC:dph] + synonym: "LDLR activity" EXACT [GOC:bf] GO:0005183 : gonadotropin hormone-releasing hormone activity GO:0006497 : protein lipidation - synonym: "protein lipidation" EXACT [] GO:0007271 : synaptic transmission, cholinergic GO:0008373 : sialyltransferase activity - def: Catalysis of the formation of sialylglycoconjugates via transfer of the sialic acid group from CMP to one of several glycoconjugate acceptors. + def: Catalysis of the transfer of sialic acid to the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. - xref: MetaCyc:2.4.99.10-RXN GO:0009025 : tagatose-bisphosphate aldolase activity - synonym: "D-tagatose-1xxx,6-bisphosphate triosephosphate lyase activity" EXACT [EC:4.1.2.40] GO:0009799 : specification of symmetry - synonym: "specification of symmetry" EXACT [GOC:dph] GO:0010017 : red or far-red light signaling pathway - synonym: "red or far red light signalling pathway" EXACT [] - synonym: "red or far-red light signaling pathway" EXACT [GOC:tb] + synonym: "red or far-red light signalling pathway" EXACT [] + synonym: "red or far red light signaling pathway" EXACT [GOC:bf, GOC:tb] GO:0010087 : phloem or xylem histogenesis - synonym: "phloem or xylem histogenesis" EXACT [GOC:tb] GO:0014069 : postsynaptic density GO:0016161 : beta-amylase activity - def: Catalysis of the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains. + def: Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains. GO:0016348 : imaginal disc-derived leg joint morphogenesis - relationship: part_of GO:0007480 + relationship: part_of GO:0036011 GO:0016985 : mannan endo-1,4-beta-mannosidase activity - synonym: "beta-1, 4-mannan 4-mannanohydrolase activity" EXACT [EC:3.2.1.78] - synonym: "beta-mannanase activity" EXACT [EC:3.2.1.78] - synonym: "endo-1,4-mannanase activity" EXACT [EC:3.2.1.78] - synonym: "endo-beta-mannanase activity" EXACT [EC:3.2.1.78] + synonym: "endo-beta-mannanase activity" BROAD [EC:3.2.1.78] + synonym: "beta-1,4-mannan 4-mannanohydrolase activity" EXACT [EC:3.2.1.78] + synonym: "endo-1,4-mannanase activity" BROAD [EC:3.2.1.78] + synonym: "beta-mannanase activity" BROAD [EC:3.2.1.78] GO:0016996 : endo-alpha-(2,8)-sialidase activity - name: endo-alpha-sialidase activity + name: endo-alpha-(2,8)-sialidase activity GO:0018532 : 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity - name: coenzyme F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity + name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity - synonym: "5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity" BROAD [] + synonym: "coenzyme F420-independent methylene-H4MPT dehydrogenase activity" EXACT [] + synonym: "F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity" EXACT [] + synonym: "coenzyme F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity" EXACT [] GO:0018537 : coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity - def: Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 1,5-dihydrocoenzyme F420 + 5,10-methylenetetrahydromethanopterin. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F(420). + def: Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420. GO:0018867 : alpha-pinene metabolic process GO:0018868 : 2-aminobenzenesulfonate metabolic process GO:0018871 : 1-aminocyclopropane-1-carboxylate metabolic process GO:0018872 : arsonoacetate metabolic process GO:0018873 : atrazine metabolic process GO:0018882 : (+)-camphor metabolic process GO:0018885 : carbon tetrachloride metabolic process GO:0018889 : 2-chloro-N-isopropylacetanilide metabolic process GO:0018898 : 2,4-dichlorobenzoate metabolic process GO:0018902 : 1,3-dichloro-2-propanol metabolic process GO:0018903 : 1,3-dichloropropene metabolic process GO:0018917 : fluorene metabolic process GO:0018920 : glyphosate metabolic process GO:0018921 : 3-hydroxybenzyl alcohol metabolic process GO:0018922 : iprodione metabolic process GO:0018923 : limonene metabolic process GO:0018928 : methyl ethyl ketone metabolic process GO:0018937 : nitroglycerin metabolic process GO:0018938 : 2-nitropropane metabolic process GO:0018952 : parathion metabolic process GO:0018955 : phenanthrene metabolic process GO:0018956 : phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene GO:0018957 : phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene GO:0018961 : pentachlorophenol metabolic process GO:0018963 : phthalate metabolic process GO:0018965 : s-triazine compound metabolic process GO:0018966 : styrene metabolic process GO:0018970 : toluene metabolic process GO:0018983 : Z-phenylacetaldoxime metabolic process GO:0019339 : parathion catabolic process GO:0019381 : atrazine catabolic process GO:0019383 : (+)-camphor catabolic process GO:0019490 : 2-aminobenzenesulfonate desulfonation GO:0021767 : mammillary body development - synonym: "mammillary body development" EXACT [] GO:0022809 : mobile ion carrier activity - def: This is a type of carrier produced by bacteria. It enable passive transport by shielding the ion that is being transported from the lipid membrane. It carries an ion across the membrane by enclosing the ion and travelling across the membrane. It does not form a fully open pore across the membrane. + def: This is a type of carrier produced by bacteria. It enables passive transport by shielding the ion that is being transported from the lipid membrane. It carries an ion across the membrane by enclosing the ion and travelling across the membrane. It does not form a fully open pore across the membrane. GO:0030089 : phycobilisome GO:0030114 : slime layer GO:0030268 : methylenetetrahydromethanopterin dehydrogenase activity - def: Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + 1,5-dihydrocoenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. + def: Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420. GO:0030570 : pectate lyase activity - def: Catalysis of the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. + def: Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. GO:0031216 : neopullulanase activity - def: Catalysis of the hydrolysis of pullulan to panose (6-a-D-glucosylmaltose). + def: Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose). GO:0031955 : short-chain fatty acid-CoA ligase activity - synonym: "short-chain fatty acid-CoA ligase activity" EXACT [] + synonym: "short-chain fatty-acid-CoA ligase activity" EXACT [GOC:bf] GO:0031956 : medium-chain fatty acid-CoA ligase activity - synonym: "medium-chain fatty acid-CoA ligase activity" EXACT [] + synonym: "medium-chain fatty-acid-CoA ligase activity" EXACT [GOC:bf] GO:0032488 : Cdc42 protein signal transduction + synonym: "Cdc42 signaling pathway" RELATED [GOC:vw] + synonym: "Cdc42 signaling" RELATED [GOC:vw] + synonym: "cdc42 signalling pathway" RELATED [GOC:vw] GO:0032620 : interleukin-17 production GO:0032799 : low-density lipoprotein receptor particle metabolic process - synonym: "low-density lipoprotein receptor particle metabolic process" EXACT [GOC:dph] + synonym: "low-density lipoprotein receptor metabolic process" EXACT [GOC:bf, GOC:dph] GO:0032803 : regulation of low-density lipoprotein particle receptor catabolic process - synonym: "regulation of low-density lipoprotein particle receptor catabolic process" EXACT [GOC:dph] + synonym: "regulation of low-density lipoprotein receptor catabolic process" EXACT [GOC:bf, GOC:dph] GO:0032805 : positive regulation of low-density lipoprotein particle receptor catabolic process - synonym: "positive regulation of low-density lipoprotein particle receptor catabolic process" EXACT [GOC:dph] + synonym: "positive regulation of low-density lipoprotein receptor catabolic process" EXACT [GOC:bf, GOC:dph] GO:0032909 : regulation of transforming growth factor beta2 production - synonym: "regulation of transforming growth factor beta2 production" EXACT [GOC:bf] + synonym: "regulation of transforming growth factor-beta2 production" EXACT [GOC:bf] GO:0032915 : positive regulation of transforming growth factor beta2 production - synonym: "positive regulation of transforming growth factor beta2 production" EXACT [GOC:bf] + synonym: "positive regulation of transforming growth factor-beta2 production" EXACT [GOC:bf] GO:0032916 : positive regulation of transforming growth factor beta3 production - synonym: "positive regulation of transforming growth factor beta3 production" EXACT [GOC:bf] + synonym: "positive regulation of transforming growth factor-beta3 production" EXACT [GOC:bf] GO:0033588 : Elongator holoenzyme complex - def: A heterohexameric protein complex that is involved in tRNA modification, and exerts indirect effects on transcriptional elongation and exocytosis. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes. + def: A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA, and exerts direct effects on transcriptional elongation and exocytosis. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes. GO:0033747 : versatile peroxidase activity - def: Catalysis of the reactions: Reactive Black 5 + hydrogen peroxide = oxidized Reactive Black 5 + 2 H2O, and donor + hydrogen peroxide = oxidized donor + 2 H2O. + def: OBSOLETE. Catalysis of the reactions: Reactive Black 5 + hydrogen peroxide = oxidized Reactive Black 5 + 2 H2O, and donor + hydrogen peroxide = oxidized donor + 2 H2O. - xref: EC:1.11.1.16 - xref: MetaCyc:RXN-8666 - xref: MetaCyc:RXN-8667 - is_a: GO:0004601 + is_obsolete: true + replaced_by: GO:0004601 + consider: GO:0052750 GO:0033786 : heptose-1-phosphate adenylyltransferase activity - name: heptose 1-phosphate adenyltransferase activity + name: heptose-1-phosphate adenylyltransferase activity + synonym: "heptose 1-phosphate adenyltransferase activity" EXACT [] GO:0033915 : mannan 1,2-(1,3)-alpha-mannosidase activity - def: Catalysis of the hydrolysis of 1,2- and 1,3-linkages in yeast mannan, releasing mannose. + def: Catalysis of the hydrolysis of 1,2- and 1,3-linkages in mannan, releasing mannose. - is_a: GO:0015923 + is_a: GO:0004559 GO:0033931 : endogalactosaminidase activity - is_a: GO:0004553 + is_a: GO:0015929 GO:0033941 : mannan exo-1,2-1,6-alpha-mannosidase activity - def: Catalysis of the hydrolysis of 1,2-alpha-D- and 1,6-alpha-D- linkages in yeast mannan, releasing D-mannose. + def: Catalysis of the hydrolysis of 1,2-alpha-D- and 1,6-alpha-D- linkages in mannan, releasing D-mannose. - is_a: GO:0015923 + is_a: GO:0004559 GO:0033947 : mannosylglycoprotein endo-beta-mannosidase activity - is_a: GO:0015923 + is_a: GO:0004567 GO:0033994 : glucuronan lyase activity - def: Catalysis of the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides. + def: Catalysis of the reaction: (1,4)-beta-D-glucuronan = an oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1,4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides. GO:0033995 : anhydrosialidase activity - def: Catalysis of the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate. + def: Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate. GO:0033996 : levan fructotransferase (DFA-IV-forming) activity - def: Catalysis of the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide. + def: Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide. GO:0033997 : inulin fructotransferase (DFA-I-forming) activity - def: Catalysis of the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide. + def: Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide. GO:0033998 : inulin fructotransferase (DFA-III-forming) activity - def: Catalysis of the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide. + def: Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide. GO:0033999 : chondroitin B lyase activity - def: Catalysis of the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). + def: Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate. + synonym: "dermatan sulfate lyase activity" EXACT [] GO:0034189 : very-low-density lipoprotein particle binding - def: Interacting selectively and non-covalently with a low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. + def: Interacting selectively and non-covalently with a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. - synonym: "very-low-density lipoprotein particle binding" EXACT [GOC:dph] + synonym: "very-low-density lipoprotein binding" EXACT [GOC:bf, GOC:dph] GO:0034444 : regulation of plasma lipoprotein particle oxidation - synonym: "regulation of plasma lipoprotein particle oxidation" EXACT [GOC:dph] + synonym: "regulation of plasma lipoprotein oxidation" EXACT [GOC:dph] GO:0034487 : vacuolar amino acid transmembrane transport - synonym: "vacuolar amino acid transmembrane transport" EXACT [] GO:0034800 : trinitrophenol dihydride denitratase activity - name: TNP dihydride denitratase activity + name: trinitrophenol dihydride denitratase activity - def: Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = 2,4-DNP hydride Meisenheimer complex + NO2. + def: Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP. + synonym: "2,4,6-trinitrophenol dihydride denitratase activity" EXACT [] + synonym: "TNP dihydride denitratase activity" EXACT [] GO:0034914 : trinitrophenol hydride denitratase activity - name: TNP hydride denitratase activity + name: trinitrophenol hydride denitratase activity - def: Catalysis of the reaction: TNP hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. + def: Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP. + synonym: "2,4,6-trinitrophenol hydride denitratase activity" EXACT [] + synonym: "TNP hydride denitratase activity" EXACT [] GO:0035287 : head segmentation - def: Partitioning the head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial). + def: Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial). + relationship: part_of GO:0060322 GO:0035288 : anterior head segmentation - def: Partitioning the head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments. + def: Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments. + relationship: part_of GO:0097065 GO:0035289 : posterior head segmentation - def: Partitioning the posterior region of the head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains. + def: Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains. GO:0035634 : response to stilbenoid GO:0035643 : L-DOPA receptor activity GO:0035801 : adrenal cortex development GO:0035878 : nail development GO:0035880 : embryonic nail plate morphogenesis GO:0035980 : invasive growth in response to nitrogen limitation - def: The growth of colonies in filamentous chains of cells as a result of a reduced availability of nitrogen. + def: OBSOLETE. The growth of colonies in filamentous chains of cells as a result of a reduced availability of nitrogen. + comment: This term was made obsolete because the GO term 'pseudohyphal growth ; GO:0007124' describes growth under nitrogen-limiting conditions. - is_a: GO:0070783 + is_obsolete: true + consider: GO:0007124 GO:0040027 : negative regulation of vulval development - synonym: "negative regulation of vulval development" EXACT [] GO:0042199 : cyanuric acid metabolic process GO:0042200 : cyanuric acid catabolic process GO:0042201 : N-cyclopropylmelamine metabolic process GO:0042202 : N-cyclopropylmelamine catabolic process GO:0042204 : s-triazine compound catabolic process GO:0042212 : cresol metabolic process GO:0042751 : estivation GO:0042807 : central vacuole GO:0042909 : acridine transport GO:0043130 : ubiquitin binding - def: Interacting selectively and non-covalently and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. + def: Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. GO:0043371 : negative regulation of CD4-positive, alpha-beta T cell differentiation - synonym: "negative regulation of CD4-positive T lymphocyte differentiation" EXACT [] - synonym: "negative regulation of CD4-positive, alpha-beta T cell differentiation" EXACT [GOC:bf] GO:0043738 : reduced coenzyme F420 dehydrogenase activity - def: Catalysis of the reaction: methanophenazine + 1,5-dihydrocoenzyme F420 = dihydromethanophenazine + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. + def: Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420. GO:0043794 : formate dehydrogenase (coenzyme F420) activity - def: Catalysis of the reaction: formate + coenzyme F420 = CO2 + 1,5-dihydrocoenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. + def: Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420. GO:0043910 : ATP:coenzyme F420 adenylyltransferase activity - name: ATP:coenzyme F420 adenyltransferase activity + name: ATP:coenzyme F420 adenylyltransferase activity + synonym: "ATP:coenzyme F420 adenyltransferase activity" EXACT [] GO:0044197 : Rel homology domain binding GO:0045135 : poly(beta-D-mannuronate) lyase activity - def: Catalysis of the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. + def: Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. GO:0046539 : histamine N-methyltransferase activity + is_a: GO:0008757 GO:0046567 : aphidicolan-16 beta-ol synthase activity - def: Catalysis of the formation of aphidicolan-16 beta-ol from geranylgeranyl diphosphate. + def: Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate. + synonym: "9-alpha-copalyl-diphosphate diphosphate-lyase (aphidicolan-16-beta-ol-forming)" EXACT [EC:4.2.3.42] + xref: EC:4.2.3.42 + xref: KEGG:R06313 + xref: MetaCyc:RXN-10631 + xref: RHEA:26216 - is_a: GO:0016829 + is_a: GO:0016838 GO:0046576 : rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity - name: rhamnogalacturonase B activity + name: rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity - def: Catalysis of the cleavage of (1,2)-alpha-L-Rhap-(1,4)-alpha-D-GalpA glycosidic linkage, generating oligosaccharides terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue. + def: Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue. + synonym: "rhamnogalacturonase B activity" EXACT [PMID:8587995] GO:0047457 : exo-(1,4)-alpha-D-glucan lyase activity - def: Catalysis of the reaction: linear alpha-glucan = 1,5-anhydro-D-fructose + beta-D-glucose. + def: Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose. GO:0047487 : oligogalacturonide lyase activity - def: Catalysis of the reaction: 4-(4-deoxy-beta-D-gluc-4-enuronosyl)-D-galacturonate = 25-dehydro-4-deoxy-D-glucuronate. + def: Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate. GO:0047489 : pectate disaccharide-lyase activity - def: Catalysis of the eliminative cleavage of 4-(4-deoxy-a-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin. + def: Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin. GO:0047490 : pectin lyase activity - def: Catalysis of the eliminative cleavage of (14)-a-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-a-D-galact-4-enuronosyl groups at their nonreducing ends. + def: Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends. GO:0047491 : poly(alpha-L-guluronate) lyase activity - def: Catalysis of the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends. + def: Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends. GO:0047492 : xanthan lyase activity - def: Catalysis of the eliminative cleavage of the terminal b-D-mannosyl-b-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-a-L-threo-hex-4-enuronosyl group at the terminus of the side-chain. + def: Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain. GO:0048265 : response to pain GO:0048749 : compound eye development GO:0050454 : coenzyme F420 hydrogenase activity - def: Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = 1,5-dihydrocoenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F(420). + def: Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = reduced coenzyme F420. GO:0050955 : thermoception GO:0050956 : electroception GO:0050958 : magnetoreception GO:0050959 : echolocation GO:0050970 : detection of electrical stimulus involved in magnetoreception GO:0050977 : magnetoreception by sensory perception of chemical stimulus GO:0050978 : magnetoreception by sensory perception of electrical stimulus GO:0050979 : magnetoreception by sensory perception of mechanical stimulus - synonym: "magnetoreception by sensory perception of mechanical stimulus" EXACT [] GO:0050980 : detection of light stimulus involved in magnetoreception GO:0051060 : pullulanase activity - def: Catalysis of the hydrolysis of (1,6)-a-D-glucosidic linkages in pullulan [a linear polymer of a-(1,6)-linked maltotriose units] and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen. + def: Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen. GO:0051461 : positive regulation of corticotropin secretion - synonym: "positive regulation of corticotropin secretion" EXACT [] GO:0051712 : positive regulation of killing of cells of other organism - synonym: "positive regulation of killing of cells of other organism" EXACT [GOC:bf] GO:0052667 : phosphomethylethanolamine N-methyltransferase activity + is_a: GO:0008757 GO:0052698 : ergothioneine metabolic process GO:0052699 : ergothioneine biosynthetic process GO:0052700 : ergothioneine catabolic process GO:0052704 : ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine GO:0052747 : sinapyl alcohol dehydrogenase activity GO:0052748 : baicalin beta-D-glucuronidase activity GO:0052749 : glucose-6-phosphate dehydrogenase (coenzyme F420) activity - def: Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + 1,5-dihydrocoenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. + def: Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420. GO:0052752 : reduced coenzyme F420:heterodisulfide oxidoreductase activity - def: Catalysis of the reaction: 1,5-dihydrocoenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. + def: Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH. + synonym: "F420H2:heterodisulfide oxidoreductase activity" EXACT [] GO:0052753 : propan-2-ol:coenzyme F420 oxidoreductase activity - def: Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + 1,5-dihydrocoenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. + def: Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420. GO:0052754 : GTP:coenzyme F420 guanyltransferase activity GO:0052755 : reduced coenzyme F420:quinone oxidoreductase activity - name: reduced coenzyme F420:2,3-dimethyl-1,4-naphthoquinone oxidoreductase activity + name: reduced coenzyme F420:quinone oxidoreductase activity - def: Catalysis of the reaction: 1,5-dihydrocoenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420, and reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone. + def: Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone. - synonym: "reduced coenzyme F420:quinone oxidoreductase activity" EXACT [] + synonym: "F420H2:quinone oxidoreductase activity" EXACT [] GO:0052756 : chitobiose phosphorylase activity - name: sulfite reductase (coenzyme F420) activity + name: chitobiose phosphorylase activity - def: Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. + def: Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-1,4-linked glucosamine units. - synonym: "coenzyme F420-dependent sulfite reductase activity" EXACT [] - synonym: "coenzyme F420-sulfite reductase activity" EXACT [] - synonym: "hydrogen-sulfide:coenzyme F420 oxidoreductase activity" EXACT [] - synonym: "sulfite:reduced coenzyme F420 reductase activity" EXACT [] - xref: EC:1.8.-.- - is_a: GO:0016667 + is_a: GO:0004645 GO:0052757 : chondroitin hydrolase activity - name: aflatoxin reductase (coenzyme F420) activity + name: chondroitin hydrolase activity - def: Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. + def: Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-]. - synonym: "aflatoxin:coenzyme F420 oxidoreductase activity" EXACT [] - synonym: "aflatoxin:reduced coenzyme F420 reductase activity" EXACT [] - synonym: "coenzyme F420-aflatoxin reductase activity" EXACT [] - synonym: "coenzyme F420-dependent aflatoxin reductase activity" EXACT [] + synonym: "chondroitin endo-beta-galactosaminidase activity" EXACT [PMID:18390555] - xref: EC:1.8.-.- + xref: EC:2.4.1.- - is_a: GO:0016667 + is_a: GO:0033931 GO:0052758 : coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity - name: F420H2:NADP+ oxidoreductase activity + name: coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity - def: Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. + def: Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction. - synonym: "F420H2:NADP oxidoreductase activity" EXACT [] - synonym: "coenzyme F420-dependent NADP reductase activity" EXACT [] - synonym: "NADP+:F420 oxidoreductase activity" EXACT [] - synonym: "coenzyme F420-dependent NADP oxidoreductase activity" EXACT [] + synonym: "coenzyme F420-dependent 2,4,6-trinitrophenol hydride transferase activity" EXACT [] + synonym: "TNP reductase activity" BROAD [] - xref: EC:1.6.-.- + xref: UM-BBD_reactionID:r1065 + xref: EC:1.3.99.- - is_a: GO:0016651 + is_a: GO:0016627 GO:0055099 : response to high density lipoprotein particle stimulus - synonym: "response to high density lipoprotein particle stimulus" EXACT [GOC:dph] GO:0060965 : negative regulation of gene silencing by miRNA - synonym: "negative regulation of gene silencing by miRNA" EXACT [GOC:pr] + synonym: "negative regulation of gene silencing by microRNA" EXACT [GOC:bf, GOC:pr] GO:0070297 : regulation of two-component signal transduction system (phosphorelay) - synonym: "regulation of two-component signal transduction system (phosphorelay)" EXACT [GOC:mah] + synonym: "regulation of two-component signal transduction system" EXACT [GOC:bf, GOC:mah] GO:0070298 : negative regulation of two-component signal transduction system (phosphorelay) - synonym: "negative regulation of two-component signal transduction system (phosphorelay)" EXACT [GOC:mah] GO:0070299 : positive regulation of two-component signal transduction system (phosphorelay) - synonym: "positive regulation of two-component signal transduction system (phosphorelay)" EXACT [GOC:mah] GO:0070326 : very-low-density lipoprotein particle receptor binding - synonym: "very-low-density lipoprotein particle receptor binding" EXACT [GOC:dph] + synonym: "very-low-density lipoprotein receptor binding" EXACT [GOC:bf, GOC:dph] GO:0070497 : 6-carboxy-5,6,7,8-tetrahydropterin synthase activity - def: Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + PPPi. + def: Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+. + xref: EC:4.2.1.- + xref: MetaCyc:RXN0-5507 - is_a: GO:0003824 + is_a: GO:0016836 GO:0070885 : negative regulation of calcineurin-NFAT signaling pathway - synonym: "negative regulation of calcineurin-NFAT signaling pathway" EXACT [GOC:mah] GO:0070886 : positive regulation of calcineurin-NFAT signaling pathway - synonym: "positive regulation of calcineurin-NFAT signaling pathway" EXACT [GOC:mah] GO:0072211 : metanephric pyramids development - synonym: "metanephric pyramids development" EXACT [GOC:mah] + synonym: "metanephric pyramid development" EXACT [GOC:mah] GO:0072496 : Pup ligase activity - synonym: "Pup ligase activity" EXACT [GOC:mah] GO:0072557 : IPAF inflammasome complex - def: A protein complex that consists of four components, NALP1, PYCARD (ASC)(27), caspase-1 and caspase-5, and includes among its functions that of being the primary mediator of susceptibility to anthrax lethal toxin. + def: A protein complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri. GO:0072558 : NLRP1 inflammasome complex - name: NALP1 inflammasome complex + name: NLRP1 inflammasome complex - def: A protein complex that consists of three components, NALP3, PYCARD and caspase-1, and includes among its functions the sensing of various stimuli including anti-viral compounds R837 and R848, bacterial mRNA, gout-associated crystals, bacterial toxins derived from Listeria monocytogenes, Staphylococcus aureus and Shigella flexneri. + def: A protein complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential. + synonym: "NALP1 inflammasome complex" EXACT [] GO:0072559 : NLRP3 inflammasome complex - name: NALP3 inflammasome complex + name: NLRP3 inflammasome complex - def: A protein complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri. + def: A protein complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus. + synonym: "NALP3 inflammasome complex" EXACT [] GO:0080101 : phosphatidyl-N-dimethylethanolamine N-methyltransferase activity + is_a: GO:0008757 GO:0090145 : mitochondrial nucleoid organization involved in mitochondrial fission - synonym: "mitochondrial nucleoid organization involved in mitochondrial fission" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] + synonym: "mitochondrial nucleoid organisation involved in mitochondrial fission" EXACT [GOC:ascb_2009, GOC:bf, GOC:dph, GOC:tb] GO:0097086 : amniotic stem cell differentiation GO:0097087 : interleukin-17A production GO:0097088 : interleukin-17F production GO:0097089 : methyl-branched fatty acid metabolic process GO:0097092 : polyacyltrehalose metabolic process GO:0097093 : polyacyltrehalose biosynthetic process GO:0097094 : craniofacial suture morphogenesis GO:0097095 : frontonasal suture morphogenesis GO:0097096 : facial suture morphogenesis GO:0097097 : nasal suture morphogenesis GO:0097099 : structural constituent of albumen GO:0097100 : supercoiled DNA binding GO:0097162 : MADS box domain binding GO:0097166 : lens epithelial cell proliferation GO:2000631 : regulation of pre-miRNA processing - synonym: "regulation of pre-miRNA processing" EXACT [GOC:obol] GO:2000817 : regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore - synonym: "regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore" EXACT [GOC:obol] GO:2000873 : regulation of histone H4 acetylation involved in response to DNA damage stimulus - synonym: "regulation of histone H4 acetylation involved in response to DNA damage stimulus" EXACT [GOC:obol] + synonym: "regulation of histone H4 acetylation involved in response to DNA damage" EXACT [GOC:bf] FILE STATS ========== Term counts for the old and new files Ontology Old file New file Change molecular function 9107 9147 +40 (9107 defined) (9147 defined) cellular component 2898 2900 +2 (2898 defined) (2900 defined) biological process 21439 21464 +25 (21439 defined) (21464 defined) Obsolete 1585 1587 +2 (4.5% of total) (4.5% of total) (+0.1%) Totals 33444 33511 +69 (+0.2%) 33444 (100.0%) defined 33511 (100.0%) defined 35029 inc. obs 35098 inc. obs