# molecular_function
20150429: LUCA_PTN000564570 contributes to ubiquitin protein ligase activity (GO:0061630)
# cellular_component
20150429: LUCA_PTN000564570 located in cytoplasm (GO:0005737)
20150429: LUCA_PTN000564570 located in SCF ubiquitin ligase complex (GO:0019005)
20150429: LUCA_PTN000564570 located in ubiquitin ligase complex (GO:0000151)
# biological_process
20150429: LUCA_PTN000564570 participates in protein ubiquitination (GO:0016567)
20150429: LUCA_PTN000564570 participates in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146)
20150429: LUCA_PTN000564570 participates in ubiquitin-dependent protein catabolic process (GO:0006511)
# Notes



Annotation inferences using phylogenetic trees

The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).