# molecular_function 20141029: Bilateria_PTN001124391 has function transposase activity (GO:0004803) 20141029: Bilateria_PTN001124391 has function endonuclease activity (GO:0004519) 20141029: Bilateria_PTN001124391 has function structure-specific DNA binding (GO:0043566) # cellular_component 20141029: Bilateria_PTN001124391 located in site of double-strand break (GO:0035861) # biological_process 20141029: Bilateria_PTN001124391 participates in DNA double-strand break processing (GO:0000729) 20141029: Bilateria_PTN001124391 participates in double-strand break repair via nonhomologous end joining (GO:0006303) 20141029: Bilateria_PTN001124391 participates in transposition, DNA-mediated (GO:0006313) # Notes Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).