# molecular_function
20140826: Has function NAD+ ADP-ribosyltransferase activity (GO:0003950) in Eukaryota_PTN000396926
20140826: Has function NAD+ ADP-ribosyltransferase activity (GO:0003950) in Eukaryota_PTN000396873
# cellular_component
20140826: Has function site of double-strand break (GO:0035861) in Opisthokonta_PTN001035536
20140826: Has function nucleus (GO:0005634) in root_PTN000396872
# biological_process
20140826: Has function protein ADP-ribosylation (GO:0006471) in Opisthokonta_PTN001035536
20140826: Has function protein ADP-ribosylation (GO:0006471) in Eukaryota_PTN000396873
20140826: Has function double-strand break repair (GO:0006302) in Opisthokonta_PTN001035536
20140826: Has function double-strand break repair (GO:0006302) in Eukaryota_PTN000396873
# Notes



Annotation inferences using phylogenetic trees

The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).