# molecular_function
20150527: Eukaryota_PTN001005210 has function endoribonuclease activity (GO:0004521)
# cellular_component
20150527: Eukaryota_PTN001005210 located in telomerase holoenzyme complex (GO:0005697)
20150527: Eukaryota_PTN001005210 located in nucleus (GO:0005634)
20150527: Eukaryota_PTN001005210 located in cytoplasm (GO:0005737)
# biological_process
20150527: Eukaryota_PTN001005210 participates in RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)
20150527: Eukaryota_PTN001005210 participates in telomere maintenance (GO:0000723)
20150527: Eukaryota_PTN001005210 participates in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)
# Notes
Did not propagate telomeric DNA binding as the paper cited shows conflicting data (human protein binds to S. cerevisiae telomeres but not very well to human telomeres; Fig 3). 
PG 2015-05-27


Annotation inferences using phylogenetic trees

The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).