This family contains human syntaxin 6, 8 and 10 and their ancestors. The root of the tree is a duplication, which gives rise to two branches. The first branch contains drosophila syntaxin 6, with a vertebrate duplication of syntaxin 6 and 10. The second branch contains a drosophila and vertebrate syntaxin 8. In the second branch, there are several arath syntaxins. Molecular function 1. Propagate the term "SNAP receptor activity" to the root. 2. Did not propagate any other terms because they seem more specific to particular genes. Cellular component Propagate the following terms to root: membrane integral to membrane SNARE complex Biological process 1. propagate intracelllular protein transport and vesicle fusion to the root. 2. Propagate retrograde transport, endosome to Golgi to the syntaxin 6 clade (PTN000272437). Here is the reason. Both human syntaxin 6 and 10 are annotated with the term. It is highly unlikely that human or vertebrate gains the function in both paralogues. It is likely that the function is evolutionarily conserved from their common ancestors.