# HISTORY 08 May 2016: Updated by: TOUCHUP-v1.18 19 Mar 2016: Updated by: TOUCHUP-v1.14 26 Apr 2016: Updated by: TOUCHUP-v1.15 # molecular_function # cellular_component 20140613: Eumetazoa_PTN001270888 is found in nucleus (GO:0005634) 20140613: Eumetazoa_PTN001270888 is found in autophagosome (GO:0005776) # biological_process 20140613: Eumetazoa_PTN001270888 participates in positive regulation of transcription, DNA-templated (GO:0045893) 20140613: Eumetazoa_PTN001270888 participates in autophagosome assembly (GO:0000045) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES In Addition to its role in transcription regulation, TP53INP1/2 has a role in autophagy by recruiting ATG8 isoforms to the pre-autophagosomal structure. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).