# HISTORY 28 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function # cellular_component 20150930: root_PTN002001020 is found in TRC complex (GO:0072380) 20150930: Bacteria _PTN002001036 is NOT found in TRC complex (GO:0072380) # biological_process 20150930: root_PTN002001020 participates in posttranslational protein targeting to membrane (GO:0006620) 20150930: Bacteria _PTN002001036 does NOT participate in posttranslational protein targeting to membrane (GO:0006620) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).