# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140909: Eukaryota_PTN000681967 has function histone serine kinase activity (GO:0035174) 20140909: node_PTN000681971 has function protein serine/threonine/tyrosine kinase activity (GO:0004712) # cellular_component 20140909: Eukaryota_PTN000681967 is found in chromosome passenger complex (GO:0032133) 20140909: Eukaryota_PTN000681967 is found in spindle microtubule (GO:0005876) 20140909: Eukaryota_PTN000681967 is found in spindle pole centrosome (GO:0031616) 20140909: Eukaryota_PTN000681967 is found in condensed nuclear chromosome, centromeric region (GO:0000780) 20140909: Eukaryota_PTN000681967 is found in spindle midzone (GO:0051233) 20140909: Fungi_PTN001219041 is NOT found in spindle pole centrosome (GO:0031616) 20140909: Viridiplantae_PTN000682053 is NOT found in spindle pole centrosome (GO:0031616) # biological_process 20140909: Eukaryota_PTN000681967 participates in mitotic spindle organization (GO:0007052) 20140909: Eukaryota_PTN000681967 participates in regulation of cytokinesis (GO:0032465) # PRUNED 27 Mar 2016: node_PTN000393701 has been pruned from tree # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES 18 Mar 2016: node_PTN000393701 has been pruned from tree A large duplication branch of TETTS genes are pruned due to poor alignment (mostly fragments). Sept. 9, 2014 - HM # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).