# HISTORY 14 Sep 2016: Saved by pascalegaudet using Paint 2.22 # molecular_function 20160902: Bilateria_PTN000660850 has function G-protein coupled receptor activity (GO:0004930) 20160902: Euteleostomi_PTN001543796 has function lysophosphatidic acid receptor activity (GO:0070915) 20160913: Tetrapoda_PTN000661089 has function cannabinoid receptor activity (GO:0004949) 20160914: Euteleostomi_PTN000660929 has function lysophosphatidic acid receptor activity (GO:0070915) 20160914: Euteleostomi_PTN000661113 has function thrombin receptor activity (GO:0015057) # cellular_component 20160902: Bilateria_PTN000660850 is found in integral component of plasma membrane (GO:0005887) # biological_process 20160913: Tetrapoda_PTN000661089 participates in activation of phospholipase C activity (GO:0007202) 20160913: Bilateria_PTN000660850 participates in positive regulation of Rho protein signal transduction (GO:0035025) 20160914: Euteleostomi_PTN000661201 participates in immune system process (GO:0002376) 20160914: Euteleostomi_PTN000661182 participates in T cell differentiation (GO:0030217) 20160914: Bilateria_PTN000660850 participates in positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway (GO:0051482) 20160914: Euteleostomi_PTN000660980 participates in positive regulation of vasodilation (GO:0045909) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).