# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
18 Mar 2016: Updated by: TOUCHUP-v1.14
27 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20140827: node_PTN000629506 has function ubiquitin protein ligase binding (GO:0031625) 
20140827: node_PTN000629506 has function ubiquitin protein ligase activity (GO:0061630) 
20140827: Eukaryota_PTN000629675 has function SUMO transferase activity (GO:0019789) 
20140827: Eukaryota_PTN000630367 has function NEDD8 transferase activity (GO:0019788) 
20140827: Eukaryota_PTN000630367 has LOST/MODIFIED function ubiquitin protein ligase binding (GO:0031625) 
20140827: Eukaryota_PTN000630367 has LOST/MODIFIED function ubiquitin protein ligase activity (GO:0061630) 
20140827: Eukaryota_PTN000629675 has LOST/MODIFIED function ubiquitin protein ligase binding (GO:0031625) 
20140827: Eukaryota_PTN000629675 has LOST/MODIFIED function ubiquitin protein ligase activity (GO:0061630) 

# cellular_component
20140827: node_PTN000629506 is found in cytoplasm (GO:0005737) 
20140827: Eukaryota_PTN000630005 is found in endoplasmic reticulum (GO:0005783) 
20140827: Eukaryota_PTN000630262 is found in nucleus (GO:0005634) 
20140827: Eukaryota_PTN000630584 is found in nucleus (GO:0005634) 
20140827: Eukaryota_PTN000629675 is found in nucleus (GO:0005634) 
20140827: Eukaryota_PTN000630069 is found in nucleus (GO:0005634) 
20140827: Eukaryota_PTN000630652 is found in nuclear chromatin (GO:0000790) 
20140827: Eukaryota_PTN000630652 is found in HULC complex (GO:0033503) 
20140827: Eukaryota_PTN000630752 is found in nucleus (GO:0005634) 
20140827: Eukaryota_PTN000629609 is found in nucleus (GO:0005634) 
20140827: Eukaryota_PTN000629507 is found in nucleus (GO:0005634) 
20140827: Eukaryota_PTN000630458 is found in nucleus (GO:0005634) 

# biological_process
20140827: Eukaryota_PTN000630520 participates in ubiquitin-dependent protein catabolic process (GO:0006511) 
20140827: Eukaryota_PTN000629793 participates in protein polyubiquitination (GO:0000209) 
20140827: Eukaryota_PTN000629793 participates in ubiquitin-dependent protein catabolic process (GO:0006511) 
20140827: Eukaryota_PTN000630005 participates in protein polyubiquitination (GO:0000209) 
20140827: Eukaryota_PTN000630005 participates in ER-associated ubiquitin-dependent protein catabolic process (GO:0030433) 
20140827: Eukaryota_PTN000630262 participates in protein K63-linked ubiquitination (GO:0070534) 
20140827: Eukaryota_PTN000630262 participates in postreplication repair (GO:0006301) 
20140827: Eukaryota_PTN000630584 participates in protein polyubiquitination (GO:0000209) 
20140827: Eukaryota_PTN000630584 participates in regulation of mitotic metaphase/anaphase transition (GO:0030071) 
20140827: Eukaryota_PTN000630584 participates in anaphase-promoting complex-dependent catabolic process (GO:0031145) 
20140827: Eukaryota_PTN000629675 participates in protein sumoylation (GO:0016925) 
20140827: Eukaryota_PTN000630069 participates in cellular response to DNA damage stimulus (GO:0006974) 
20140827: Eukaryota_PTN000630069 participates in protein polyubiquitination (GO:0000209) 
20140827: Eukaryota_PTN000630651 participates in protein polyubiquitination (GO:0000209) 
20140827: Eukaryota_PTN000630651 participates in DNA repair (GO:0006281) 
20140827: Eukaryota_PTN000630651 participates in histone ubiquitination (GO:0016574) 
20140827: Eukaryota_PTN000630651 participates in proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) 
20140827: Eukaryota_PTN000630752 participates in ubiquitin-dependent protein catabolic process (GO:0006511) 
20140827: Eukaryota_PTN000630752 participates in protein polyubiquitination (GO:0000209) 
20140827: Eukaryota_PTN000629609 participates in proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) 
20140827: Eukaryota_PTN000629609 participates in protein polyubiquitination (GO:0000209) 
20140827: Eukaryota_PTN000629507 participates in postreplication repair (GO:0006301) 
20140827: Eukaryota_PTN000629507 participates in protein K63-linked ubiquitination (GO:0070534) 
20140827: Eukaryota_PTN000630458 participates in proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) 
20140827: Eukaryota_PTN000630458 participates in protein polyubiquitination (GO:0000209) 
20140827: Eukaryota_PTN000630367 participates in protein neddylation (GO:0045116) 
20140827: Eukaryota_PTN000629795 participates in proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).