# HISTORY 12 Jan 2017: Saved by pgaudet using Paint v2.29 on 12 Jan 2017 using PANTHER version UPL 11.0 # molecular_function 20170112: Euteleostomi_PTN001154800 has function transcription coactivator activity (GO:0003713) 20170112: Deuterostomia_PTN000596121 has function Arp2/3 complex binding (GO:0071933) 20170112: Euteleostomi_PTN000596145 has function GTP-Rho binding (GO:0017049) # cellular_component 20170112: Deuterostomia_PTN001154804 is found in nucleus (GO:0005634) 20170112: Deuterostomia_PTN001154804 is found in cytoplasm (GO:0005737) 20170112: Euteleostomi_PTN001154800 is found in nucleus (GO:0005634) 20170112: Eumetazoa_PTN001154798 is found in cytoplasm (GO:0005737) 20170112: Euteleostomi_PTN000596145 is found in endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116) # biological_process 20170112: Euteleostomi_PTN001154800 participates in intrinsic apoptotic signaling pathway by p53 class mediator (GO:0072332) 20170112: Deuterostomia_PTN000596121 participates in Arp2/3 complex-mediated actin nucleation (GO:0034314) 20170112: Euteleostomi_PTN001154800 participates in 'de novo' actin filament nucleation (GO:0070060) 20170112: Eumetazoa_PTN001154798 participates in cell cycle arrest (GO:0007050) 20170112: Euteleostomi_PTN001154800 participates in positive regulation of apoptotic process (GO:0043065) 20170112: Euteleostomi_PTN001154800 participates in positive regulation of sequence-specific DNA binding transcription factor activity (GO:0051091) 20170112: Euteleostomi_PTN000596145 participates in ER to Golgi vesicle-mediated transport (GO:0006888) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).