# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 17 Mar 2016: Updated by: TOUCHUP-v1.14 26 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150629: root_PTN000561878 has function GTPase activity (GO:0003924) 20150629: node_PTN000754007 has function translation elongation factor activity (GO:0003746) 20150629: cellular organisms_PTN000562153 has function translation initiation factor activity (GO:0003743) 20150629: Eukaryota_PTN000562490 has function translation elongation factor activity (GO:0003746) 20150629: Eukaryota_PTN000562411 has function translation release factor activity (GO:0003747) 20150629: Bacteria _PTN000562733 has function selenocysteine insertion sequence binding (GO:0035368) 20150629: node_PTN001500717 has function translation elongation factor activity (GO:0003746) 20150629: node_PTN000563278 has function translation release factor activity, codon nonspecific (GO:0016150) # cellular_component 20150629: root_PTN000561878 is found in intracellular (GO:0005622) 20150629: Eukaryota_PTN000563009 is found in mitochondrion (GO:0005739) 20150629: Eukaryota_PTN000563148 is found in mitochondrion (GO:0005739) 20150629: Eukaryota_PTN000562411 is found in translation release factor complex (GO:0018444) 20150629: Eukaryota_PTN000562037 is found in mitochondrion (GO:0005739) 20150629: Eukaryota_PTN000561955 is found in mitochondrion (GO:0005739) # biological_process 20150629: root_PTN000561878 participates in translation (GO:0006412) 20150629: Eukaryota_PTN000563009 participates in mitochondrial translational elongation (GO:0070125) 20150629: Eukaryota_PTN000562984 participates in ribosome disassembly (GO:0032790) 20150629: Eukaryota_PTN000562912 participates in mature ribosome assembly (GO:0042256) 20150629: cellular organisms_PTN000562153 participates in formation of translation preinitiation complex (GO:0001731) 20150629: Eukaryota_PTN000562411 participates in cytoplasmic translational termination (GO:0002184) 20150629: Eukaryota_PTN000562336 participates in ribosome disassembly (GO:0032790) 20150629: Bacteria _PTN000562733 participates in selenocysteine incorporation (GO:0001514) 20150629: Bacteria _PTN000563272 participates in sulfur compound metabolic process (GO:0006790) 20150629: node_PTN001500717 participates in translational elongation (GO:0006414) 20150629: Eukaryota_PTN000562037 participates in mitochondrial translational elongation (GO:0070125) 20150629: Eukaryota_PTN000561955 participates in mitochondrial translational initiation (GO:0070124) 20150629: Eukaryota_PTN000562846 does NOT participate in translation (GO:0006412) 20150629: Eukaryota_PTN000562912 does NOT participate in translation (GO:0006412) 20150629: Bacteria _PTN000563272 does NOT participate in translation (GO:0006412) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).