# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 17 Mar 2016: Updated by: TOUCHUP-v1.14 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150212: root_PTN000546859 has function phosphatase activity (GO:0016791) 20150212: node_PTN001126135 has function sedoheptulose-bisphosphatase activity (GO:0050278) # cellular_component 20150212: root_PTN000546859 is found in cytosol (GO:0005829) # biological_process # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Since this is a dephophatase family, protein dephosphatase and dephosphorylation are redundant. This BP term was not propagated. Most of the BP terms are from IMP. No BP terms are propagated. It seems that the plant sedheptulose 1,7-bisphophatase genes are in PTHR11556. Should they be merged? Feb. 12, 2015, HM # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).