# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
17 Mar 2016: Updated by: TOUCHUP-v1.14
17 Mar 2016: Updated by: TOUCHUP-v1.14
26 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20151109: root_PTN000539981 has function protein serine/threonine kinase activity (GO:0004674) 
20151109: Pentapetalae_PTN001884390 has function ubiquitin-protein transferase activity (GO:0004842) 
20151109: Euteleostomi_PTN000540022 has function phosphatase regulator activity (GO:0019208) 
20151109: Opisthokonta_PTN001121691 has function AP-2 adaptor complex binding (GO:0035612) 

# cellular_component
20151109: Eukaryota_PTN000540112 is found in cytoplasm (GO:0005737) 
20151109: Pentapetalae_PTN001884390 is found in trans-Golgi network (GO:0005802) 
20151109: Pentapetalae_PTN001884390 is found in early endosome (GO:0005769) 
20151109: Eukaryota_PTN001884433 is found in nucleus (GO:0005634) 
20151109: Eukaryota_PTN000539982 is found in cytoplasm (GO:0005737) 

# biological_process
20151109: root_PTN000539981 participates in protein phosphorylation (GO:0006468) 
20151109: Fungi_PTN001121785 participates in regulation of vacuole fusion, non-autophagic (GO:0032889) 
20151109: Fungi_PTN001121785 participates in vacuolar protein processing (GO:0006624) 
20151109: Amniota_PTN000540120 participates in cellular response to transforming growth factor beta stimulus (GO:0071560) 
20151109: Pentapetalae_PTN001884390 participates in late endosome to vacuole transport (GO:0045324) 
20151109: Pentapetalae_PTN001884390 participates in negative regulation of abscisic acid-activated signaling pathway (GO:0009788) 
20151109: Euteleostomi_PTN000540022 participates in regulation of bone mineralization (GO:0030500) 
20151109: Eukaryota_PTN000539982 participates in regulation of endocytosis (GO:0030100) 
20151109: Fungi_PTN001121721 participates in actin filament organization (GO:0007015) 
20151109: Fungi_PTN001121721 participates in actin cortical patch assembly (GO:0000147) 
20151109: Opisthokonta_PTN001121691 participates in positive regulation of Notch signaling pathway (GO:0045747) 
20151109: Opisthokonta_PTN001121691 participates in regulation of clathrin-mediated endocytosis (GO:2000369) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).