# HISTORY
24 Aug 2016: Saved by mfeuerma using Paint 2.22

# molecular_function
20160824: saccharomyceta_PTN000494028 has function ubiquitin protein ligase binding (GO:0031625) 
20160824: Dikarya_PTN001092429 has function sphingolipid binding (GO:0046625) 
20160824: Dikarya_PTN001092429 has function phosphatidylinositol-3-phosphate binding (GO:0032266) 
20160824: Dikarya_PTN001092429 has function phosphatidylinositol-3,5-bisphosphate binding (GO:0080025) 
20160824: Dikarya_PTN001092429 has function phosphatidic acid binding (GO:0070300) 

# cellular_component
20160824: Pristionchus pacificus_PPA26847 is NOT found in fungal-type vacuole lumen (GO:0000328) 
20160824: Pristionchus pacificus_PPA23681 is NOT found in fungal-type vacuole lumen (GO:0000328) 
20160824: saccharomyceta_PTN000494028 is found in fungal-type vacuole lumen (GO:0000328) 
20160824: saccharomyceta_PTN000494028 is found in fungal-type vacuole membrane (GO:0000329) 
20160824: Dikarya_PTN001472415 is found in fungal-type vacuole lumen (GO:0000328) 
20160824: Dikarya_PTN001472415 is found in fungal-type vacuole membrane (GO:0000329) 
20160824: Dikarya_PTN001092429 is found in plasma membrane (GO:0005886) 

# biological_process
20160824: saccharomyceta_PTN000494028 participates in endosome transport via multivesicular body sorting pathway (GO:0032509) 
20160824: saccharomyceta_PTN000494028 participates in cellular protein catabolic process (GO:0044257) 
20160824: Dikarya_PTN001092429 participates in regulation of membrane potential (GO:0042391) 
20160824: Dikarya_PTN001092429 participates in cation transport (GO:0006812) 
20160824: Dikarya_PTN001092429 participates in cellular response to drug (GO:0035690) 
20160824: node_PTN001472431 participates in response to abscisic acid (GO:0009737) 
20160824: node_PTN001472431 participates in response to cold (GO:0009409) 
20160824: node_PTN001472431 participates in response to salt stress (GO:0009651) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
MAF: Highly divergent functions from one node to the other impairs inference at the tree level.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).