# HISTORY 12 Jan 2017: Saved by pgaudet using Paint v2.29 on 12 Jan 2017 using PANTHER version UPL 11.0 # molecular_function 20170112: Bilateria_PTN000468430 has function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding (GO:0001077) 20170112: Bilateria_PTN000468430 has function RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978) # cellular_component 20170112: Bilateria_PTN000468430 is found in nucleus (GO:0005634) # biological_process 20170112: Chordata_PTN000468432 participates in somitogenesis (GO:0001756) 20170112: Chordata_PTN000468432 participates in embryonic pattern specification (GO:0009880) 20170112: Chordata_PTN000468432 participates in mesoderm formation (GO:0001707) 20170112: Euteleostomi_PTN000468457 participates in heart morphogenesis (GO:0003007) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).