# HISTORY
26 Mar 2016: Updated by: TOUCHUP-v1.15
16 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function

# cellular_component

# biological_process
20150618: Mammalia_PTN000425257 participates in protease localization to mast cell secretory granule (GO:0033368) 
20150618: Mammalia_PTN000425257 participates in negative regulation of bone mineralization (GO:0030502) 
# PRUNED

26 Mar 2016: sordariomyceta_PTN001820042 has been pruned from tree

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
16 Mar 2016: sordariomyceta_PTN001820042 has been pruned from tree
Review PMID:24455486
Role in apoptosis not clear; but probably at regulation level.
Annotated PG 2015-06-18

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).