# HISTORY
26 Mar 2016: Updated by: TOUCHUP-v1.15
16 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20140417: Eukaryota_PTN000785381 has function tubulin binding (GO:0015631) 

# cellular_component
20140417: Eukaryota_PTN000785381 is found in cilium (GO:0005929) 
20140417: Eukaryota_PTN000785381 is found in intraciliary transport particle B (GO:0030992) 
20140417: Eukaryota_PTN000785381 is found in centrosome (GO:0005813) 

# biological_process
20140417: Eukaryota_PTN000785381 participates in intraciliary transport (GO:0042073) 
20140418: Eukaryota_PTN000785381 participates in cilium assembly (GO:0042384) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
Background & Phylogeny
This family comprises the conserved Ift81 subunit of the eukaryotic Intraflagellar Transport Complex B (IFT B) which is involved in anterograde transport within the eukaryotic cilium/flagellum in conjunction with a kinesin-2 motor. Originally characterized in Chlamydomonas reinhardtii, with subsequent work in C. elegans, all of the IFT complex protein genes identified in Chlamydomonas and Caenorhabditis are conserved in mammals (PMID:19253336). Ift81 and Ift74 form a subcomplex that specifically binds to tubulin, one of the major cargo proteins for intraciliary transport during the cilium assembly (PMID:23990561).

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).