# HISTORY 06 May 2016: Saved by mfeuerma using Paint 2.0-beta18 # molecular_function 20160506: Euteleostomi_PTN000392309 has function morphogen activity (GO:0016015) # cellular_component 20160506: Euteleostomi_PTN000392309 is found in extracellular space (GO:0005615) # biological_process 20160506: Euteleostomi_PTN000392309 participates in negative regulation of activin receptor signaling pathway (GO:0032926) 20160506: Euteleostomi_PTN000392309 participates in negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry (GO:1900176) 20160506: Euteleostomi_PTN000392309 participates in sequestering of BMP in extracellular matrix (GO:0035582) 20160506: Euteleostomi_PTN000392309 participates in determination of heart left/right asymmetry (GO:0061371) 20160506: Euteleostomi_PTN000392309 participates in signal transduction involved in regulation of gene expression (GO:0023019) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).