# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150116: Mammalia_PTN000392086 has function tumor necrosis factor receptor superfamily binding (GO:0032813) # cellular_component 20150116: Mammalia_PTN000392086 is found in cell surface (GO:0009986) # biological_process 20150116: Mammalia_PTN000392086 participates in tumor necrosis factor-mediated signaling pathway (GO:0033209) 20150116: Mammalia_PTN000392086 participates in T cell proliferation involved in immune response (GO:0002309) 20150116: Mammalia_PTN000392086 participates in cell-cell signaling (GO:0007267) 20150116: Mammalia_PTN000392086 participates in regulation of T cell proliferation (GO:0042129) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).