# HISTORY 09 Jul 2016: Updated by: TOUCHUP-v1.19 # molecular_function 20160428: root_PTN001804925 has function tRNA binding (GO:0000049) 20160428: node_PTN000382878 has function tRNA (guanine) methyltransferase activity (GO:0016423) # cellular_component 20160428: node_PTN001804941 is found in cytosol (GO:0005829) # biological_process 20160428: node_PTN000382878 participates in tRNA methylation (GO:0030488) 20160428: node_PTN001804941 participates in tRNA 4-thiouridine biosynthesis (GO:0002937) 20160428: node_PTN001804941 participates in thiazole biosynthetic process (GO:0052837) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).