# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
16 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20140103: Eukaryota_PTN000374345 contributes to function RNA polymerase I activity (GO:0001054) 

# cellular_component
20140103: Eukaryota_PTN000374345 is found in DNA-directed RNA polymerase I complex (GO:0005736) 

# biological_process

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
this family comprises a conserved subunit rpa49 of the multisubunit dna-dependent rna polymerase i in eukaryotes. it is thought to share some structural and functional similarity with the rap30 subunit of the tfiif transcription factor for rnap ii, though the sequence similarity alone is not sufficient to group them. there is no corresponding subunit in the multisubunit rna polymerases of archaea or bacteria.
Annotation Comment
-----------------
No direct propagations were made for BP since the appropriate term can all be inferred by the Function-Process links from the propagated MF term.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).