# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140815: Boreoeutheria_PTN000370309 has function cytokine activity (GO:0005125) # cellular_component 20140815: Boreoeutheria_PTN000370309 is found in extracellular space (GO:0005615) # biological_process 20140815: Boreoeutheria_PTN000370309 participates in negative regulation of cell proliferation (GO:0008285) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Successfully disputed BHFL P13725 GO:0005900 IDA (ECO:0000314) PMID:8999038 (oncostatin-M receptor complex); a ligand is not part of a receptor complex (https://sourceforge.net/p/geneontology/ontology-requests/11078/) # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).