# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function # cellular_component 20140728: Eukaryota_PTN000365417 is found in COP9 signalosome (GO:0008180) 20140728: Opisthokonta_PTN000365350 is found in proteasome regulatory particle (GO:0005838) # biological_process 20140728: Eukaryota_PTN000365417 participates in cullin deneddylation (GO:0010388) 20140728: Eukaryota_PTN000365348 participates in proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) # PRUNED 25 Mar 2016: Saccharomycetaceae_PTN001423084 has been pruned from tree # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES 16 Mar 2016: Saccharomycetaceae_PTN001423084 has been pruned from tree Yesat COP9 signalosome complex subunit 11 (P40512) in the 26S proteosome non-ATPase regulatory subunit 6 clade. Pruned the sequences. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).