# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 16 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140926: Amniota_PTN000364583 has function growth hormone-releasing hormone activity (GO:0016608) 20140926: Amniota_PTN000364583 has function ghrelin receptor binding (GO:0031768) # cellular_component 20140926: Amniota_PTN000364583 is found in extracellular space (GO:0005615) # biological_process 20140926: Amniota_PTN000364583 participates in regulation of response to food (GO:0032095) 20140926: Amniota_PTN000364583 participates in positive regulation of protein tyrosine kinase activity (GO:0061098) 20140926: Amniota_PTN000364583 participates in hormone-mediated signaling pathway (GO:0009755) 20140926: Amniota_PTN000364583 participates in negative regulation of inflammatory response (GO:0050728) 20140926: Amniota_PTN000364583 participates in gastric acid secretion (GO:0001696) 20140926: Amniota_PTN000364583 participates in positive regulation of growth hormone secretion (GO:0060124) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).