# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150805: Bilateria_PTN001790569 has function structural constituent of muscle (GO:0008307) 20150805: Bilateria_PTN001790569 has function actin filament binding (GO:0051015) 20150805: Bilateria_PTN001790569 has function muscle alpha-actinin binding (GO:0051371) 20150805: Bilateria_PTN001790569 has function structural molecule activity conferring elasticity (GO:0097493) # cellular_component 20150805: Bilateria_PTN001790569 is found in Z disc (GO:0030018) 20150805: Bilateria_PTN001790569 is found in muscle myosin complex (GO:0005859) 20150805: Bilateria_PTN001790569 is found in M band (GO:0031430) 20150805: Bilateria_PTN001790569 is found in striated muscle thin filament (GO:0005865) # biological_process 20150805: Bilateria_PTN001790569 participates in striated muscle contraction (GO:0006941) 20150805: Bilateria_PTN001790569 participates in striated muscle myosin thick filament assembly (GO:0071688) 20150805: Bilateria_PTN001790569 participates in sarcomere organization (GO:0045214) 20150805: Bilateria_PTN001790569 participates in actin filament organization (GO:0007015) 20150805: node_PTN001418633 participates in skeletal muscle thin filament assembly (GO:0030240) 20150805: node_PTN001418633 participates in cardiac muscle tissue morphogenesis (GO:0055008) 20150805: node_PTN001418633 participates in cardiac myofibril assembly (GO:0055003) 20150805: node_PTN001418633 participates in skeletal muscle myosin thick filament assembly (GO:0030241) 20150805: node_PTN001418633 participates in cardiac muscle fiber development (GO:0048739) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).