# HISTORY 21 Sep 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160921: Eukaryota_PTN001000243 contributes to function succinate dehydrogenase (ubiquinone) activity (GO:0008177) 20160921: Eukaryota_PTN001000243 has function heme binding (GO:0020037) 20160921: Eukaryota_PTN001000243 has function ubiquinone binding (GO:0048039) 20160921: Saccharomycetaceae_PTN000330887 has LOST/MODIFIED function heme binding (GO:0020037) 20160921: Saccharomycetaceae_PTN000330887 has LOST/MODIFIED function succinate dehydrogenase (ubiquinone) activity (GO:0008177) 20160921: Saccharomycetaceae_PTN000330887 has LOST/MODIFIED function ubiquinone binding (GO:0048039) 20160921: Saccharomycetaceae_PTN000330887 contributes to function protein channel activity (GO:0015266) # cellular_component 20160921: Eukaryota_PTN001000243 is found in mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) (GO:0005749) 20160921: Saccharomycetaceae_PTN000330887 is NOT found in mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) (GO:0005749) 20160921: Saccharomycetaceae_PTN000330887 is found in mitochondrial inner membrane protein insertion complex (GO:0042721) # biological_process 20160921: Eukaryota_PTN001000243 participates in tricarboxylic acid cycle (GO:0006099) 20160921: Eukaryota_PTN001000243 participates in mitochondrial electron transport, succinate to ubiquinone (GO:0006121) 20160921: Saccharomycetaceae_PTN000330887 does NOT participate in mitochondrial electron transport, succinate to ubiquinone (GO:0006121) 20160921: Saccharomycetaceae_PTN000330887 does NOT participate in tricarboxylic acid cycle (GO:0006099) 20160921: Saccharomycetaceae_PTN000330887 participates in protein import into mitochondrial inner membrane (GO:0045039) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).