# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150717: root_PTN000327874 has function protein-lysine N-methyltransferase activity (GO:0016279) 20150717: Eukaryota_PTN001777757 has function histone methyltransferase activity (H3-K4 specific) (GO:0042800) 20150717: Eukaryota_PTN001777757 has function histone methyltransferase activity (H3-K36 specific) (GO:0046975) 20150717: Eukaryota_PTN001777757 has function transcription coactivator activity (GO:0003713) 20150717: Opisthokonta_PTN000998305 has function NF-kappaB binding (GO:0051059) # cellular_component 20150717: Eukaryota_PTN001777757 is found in nuclear chromatin (GO:0000790) 20150717: Eukaryota_PTN000327876 is found in nucleolus (GO:0005730) 20150717: Opisthokonta_PTN001777785 is found in cytosol (GO:0005829) 20150717: Opisthokonta_PTN001777785 is found in nucleus (GO:0005634) 20150717: Magnoliophyta_PTN001409708 is found in chloroplast stroma (GO:0009570) 20150717: Eukaryota_PTN001777938 is found in nucleus (GO:0005634) 20150717: Magnoliophyta_PTN001777955 is found in chloroplast thylakoid (GO:0009534) 20150717: Magnoliophyta_PTN001777955 is found in plastid chromosome (GO:0009508) 20150717: Magnoliophyta_PTN001777955 is found in plastid-encoded plastid RNA polymerase complex (GO:0000427) # biological_process 20150717: root_PTN000327874 participates in peptidyl-lysine monomethylation (GO:0018026) 20150717: Eukaryota_PTN001777757 participates in peptidyl-lysine dimethylation (GO:0018027) 20150717: Eukaryota_PTN001777757 participates in peptidyl-lysine trimethylation (GO:0018023) 20150717: Eukaryota_PTN001777757 participates in positive regulation of transcription from RNA polymerase II promoter (GO:0045944) 20150717: Eukaryota_PTN001777757 participates in histone H3-K4 methylation (GO:0051568) 20150717: Eukaryota_PTN001777757 participates in histone H3-K36 methylation (GO:0010452) 20150717: Eukaryota_PTN000327876 participates in ribosome biogenesis (GO:0042254) 20150717: Eukaryota_PTN000327876 participates in peptidyl-lysine trimethylation (GO:0018023) 20150717: Opisthokonta_PTN000998305 participates in regulation of inflammatory response (GO:0050727) 20150717: Opisthokonta_PTN000998305 participates in negative regulation of NF-kappaB transcription factor activity (GO:0032088) 20150717: Viridiplantae_PTN000328020 participates in peptidyl-lysine trimethylation (GO:0018023) 20150717: Eukaryota_PTN001777938 participates in peptidyl-lysine dimethylation (GO:0018027) 20150717: Eukaryota_PTN001777938 participates in regulation of cytoplasmic translation in response to stress (GO:1990497) 20150717: Magnoliophyta_PTN001777955 participates in transcription from plastid promoter (GO:0042793) 20150717: Magnoliophyta_PTN001777955 participates in chloroplast organization (GO:0009658) 20150717: Magnoliophyta_PTN001777955 participates in thylakoid membrane organization (GO:0010027) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).