# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20151117: Eukaryota_PTN000327778 has function structural constituent of nuclear pore (GO:0017056) # cellular_component 20151117: Eukaryota_PTN000327778 is found in nuclear pore transmembrane ring (GO:0070762) 20151118: Eukaryota_PTN000327778 is found in spindle pole body (GO:0005816) 20151118: Eumetazoa_PTN000998247 is NOT found in spindle pole body (GO:0005816) 20151118: Embryophyta_PTN000998273 is NOT found in spindle pole body (GO:0005816) # biological_process 20151118: Eukaryota_PTN000327778 participates in spindle pole body duplication (GO:0030474) 20151118: Eukaryota_PTN000327778 participates in establishment of spindle pole body localization to nuclear envelope (GO:0071790) 20151118: Eukaryota_PTN000327778 participates in nuclear pore organization (GO:0006999) 20151118: Eumetazoa_PTN000998247 does NOT participate in spindle pole body duplication (GO:0030474) 20151118: Eumetazoa_PTN000998247 does NOT participate in establishment of spindle pole body localization to nuclear envelope (GO:0071790) 20151118: Embryophyta_PTN000998273 does NOT participate in spindle pole body duplication (GO:0030474) 20151118: Embryophyta_PTN000998273 does NOT participate in establishment of spindle pole body localization to nuclear envelope (GO:0071790) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES This family comprises NDC1, a POM, which is an integral membrane protein of the nuclear envelope membrane domain of the nuclear pore complex [Hoelz et al. 2011 (PMID:21495847), Aitchison and Rout 2012 (PMID:22419078), and Kabachinski and Schwartz 2015 (PMID:26046137)]. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).