# HISTORY 12 Jan 2017: Saved by mfeuerma using Paint 2.28 on 12 Jan 2017 using PANTHER version UPL 11.0 # molecular_function 20170112: Eukaryota_PTN000323131 has function mechanically-gated ion channel activity (GO:0008381) 20170112: Eukaryota_PTN000323131 has function cation channel activity (GO:0005261) # cellular_component 20170112: Eukaryota_PTN000323131 is found in membrane (GO:0016020) 20170112: Bilateria_PTN000323194 is found in plasma membrane (GO:0005886) 20170112: Euteleostomi_PTN000323197 is found in endoplasmic reticulum (GO:0005783) # biological_process 20170112: Eukaryota_PTN000323131 participates in detection of mechanical stimulus (GO:0050982) 20170112: Eukaryota_PTN000323131 participates in cellular response to mechanical stimulus (GO:0071260) 20170112: Eukaryota_PTN000323131 participates in regulation of membrane potential (GO:0042391) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).