# HISTORY 04 Aug 2016: Updated by: TOUCHUP-v1.21 # molecular_function 20160428: root_PTN001773163 has function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (GO:0016706) 20160428: root_PTN001773163 has function iron ion binding (GO:0005506) 20160428: Eukaryota_PTN000318179 has function histone demethylase activity (H3-K4 specific) (GO:0032453) 20160428: Eukaryota_PTN000318179 has function histone demethylase activity (H3-K36 specific) (GO:0051864) # cellular_component 20160428: node_PTN000991806 is found in nucleus (GO:0005634) # biological_process 20160428: root_PTN001773163 participates in post-translational protein modification (GO:0043687) 20160428: root_PTN001773163 participates in ribosome biogenesis (GO:0042254) 20160428: root_PTN001773163 participates in peptidyl-amino acid modification (GO:0018193) 20160428: node_PTN000991806 participates in negative regulation of transcription, DNA-templated (GO:0045892) 20160428: Eukaryota_PTN000318179 participates in chromatin remodeling (GO:0006338) 20160428: Bacteria _PTN001773197 participates in peptidyl-arginine hydroxylation (GO:0030961) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).