# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20140131: Eukaryota_PTN000299878 contributes to function RNA polymerase III activity (GO:0001056) # cellular_component 20140131: Eukaryota_PTN000299878 is found in DNA-directed RNA polymerase III complex (GO:0005666) # biological_process # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES this family comprises a conserved subunit, referred to as rpc34, polr3f, or rpc6, of the multisubunit dna-dependent rna polymerase iii enzyme in eukaryotes. this subunit is unique to rna polymerase iii without a corresponding subunit in rna polymerases i or ii (pmid:18573085). # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).