# HISTORY 28 Jul 2016: Saved by pascalegaudet using Paint 2.21 # molecular_function 20160728: Eukaryota_PTN000289179 has function protein disulfide oxidoreductase activity (GO:0015035) 20160728: Eukaryota_PTN000289179 has function protein disulfide isomerase activity (GO:0003756) # cellular_component 20160728: Eukaryota_PTN000289179 is found in endoplasmic reticulum membrane (GO:0005789) # biological_process 20160728: Eukaryota_PTN000289179 participates in cellular protein modification process (GO:0006464) 20160728: Eukaryota_PTN000289179 participates in protein folding in endoplasmic reticulum (GO:0034975) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).