# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140829: Eukaryota_PTN000281557 has function O-acyltransferase activity (GO:0008374) # cellular_component 20140829: Eukaryota_PTN000281557 is found in intrinsic component of membrane (GO:0031224) 20140829: Eukaryota_PTN000281558 is found in mitochondrial membrane (GO:0031966) # biological_process 20140829: Eukaryota_PTN000281558 participates in cardiolipin acyl-chain remodeling (GO:0035965) 20140829: Eukaryota_PTN000281558 participates in inner mitochondrial membrane organization (GO:0007007) 20140829: Euteleostomi_PTN000281563 participates in heart development (GO:0007507) 20140829: Viridiplantae_PTN000281607 participates in glycerophospholipid metabolic process (GO:0006650) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).