# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 15 Mar 2016: Updated by: TOUCHUP-v1.14 25 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20151009: root_PTN000272698 has function serine-type endopeptidase activity (GO:0004252) # cellular_component 20151009: node_PTN000272697 is found in mitochondrial inner membrane peptidase complex (GO:0042720) 20151009: node_PTN001750355 is found in chloroplast thylakoid membrane (GO:0009535) 20151009: Bacteria _PTN000272836 is found in integral component of plasma membrane (GO:0005887) 20151009: Cyanobacteria_PTN000962883 is NOT found in chloroplast thylakoid membrane (GO:0009535) 20151009: node_PTN001750355 is NOT found in mitochondrial inner membrane peptidase complex (GO:0042720) # biological_process 20151009: root_PTN000272698 participates in signal peptide processing (GO:0006465) 20151009: node_PTN000272697 participates in mitochondrial respiratory chain complex assembly (GO:0033108) 20151009: node_PTN000272697 participates in protein processing involved in protein targeting to mitochondrion (GO:0006627) 20151009: node_PTN001750355 participates in thylakoid membrane organization (GO:0010027) 20151009: Cyanobacteria_PTN000962883 does NOT participate in thylakoid membrane organization (GO:0010027) 20151009: node_PTN001750355 does NOT participate in mitochondrial respiratory chain complex assembly (GO:0033108) 20151009: node_PTN001750355 does NOT participate in protein processing involved in protein targeting to mitochondrion (GO:0006627) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).