# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150619: root_PTN000258719 has function phosphoprotein phosphatase activity (GO:0004721) # cellular_component 20150619: Eukaryota_PTN000258720 is found in mitochondrial inner membrane presequence translocase complex (GO:0005744) # biological_process 20150619: Eukaryota_PTN000258720 participates in protein import into mitochondrial matrix (GO:0030150) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES I would have liked to stop the propagation of phosphoprotein phosphatase activity (GO:0004721) to root_PTN000258719, since UniProt has for the human ortholog Q3ZCQ8 "Has some phosphatase activity in vitro; however such activity may not be relevant in vivo", but PAINT does not allow to do that right now. Annotated PG 2015-06-19 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).