# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20160229: Euteleostomi_PTN000257221 has function RNA polymerase II core binding (GO:0000993) 20160229: Euteleostomi_PTN000257170 has function DEAD/H-box RNA helicase binding (GO:0017151) 20160229: Tetrapoda_PTN000257171 has function protein kinase A regulatory subunit binding (GO:0034237) 20160229: Tetrapoda_PTN000257171 has LOST/MODIFIED function DEAD/H-box RNA helicase binding (GO:0017151) # cellular_component 20160229: Euteleostomi_PTN000257221 is found in DBIRD complex (GO:0044609) 20160229: Euteleostomi_PTN000257221 is found in nuclear matrix (GO:0016363) 20160229: Euteleostomi_PTN000257170 is found in nuclear matrix (GO:0016363) # biological_process 20160229: Euteleostomi_PTN000257221 participates in RNA splicing (GO:0008380) 20160229: Euteleostomi_PTN000257221 participates in regulation of DNA-templated transcription, elongation (GO:0032784) 20160229: Tetrapoda_PTN000257171 participates in mitotic nuclear division (GO:0007067) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).