# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20160114: Eukaryota_PTN000255549 contributes to function ATP-dependent DNA helicase activity (GO:0004003) 20160114: Eukaryota_PTN000255549 has function damaged DNA binding (GO:0003684) # cellular_component 20160114: Eukaryota_PTN000255549 is found in nuclear chromosome, telomeric region (GO:0000784) 20160114: Eukaryota_PTN000255549 is found in Mre11 complex (GO:0030870) # biological_process 20160114: Eukaryota_PTN000255549 participates in signal transduction in response to DNA damage (GO:0042770) 20160114: Eukaryota_PTN000255549 participates in mitotic G2 DNA damage checkpoint (GO:0007095) 20160114: Eukaryota_PTN000255549 participates in telomere capping (GO:0016233) 20160114: Eukaryota_PTN000255549 participates in double-strand break repair via homologous recombination (GO:0000724) 20160114: Eukaryota_PTN000255549 participates in DNA duplex unwinding (GO:0032508) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).