# HISTORY 25 Aug 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160825: node_PTN000246442 has function growth factor activity (GO:0008083) 20160825: Euteleostomi_PTN001738334 has function vascular endothelial growth factor receptor 1 binding (GO:0043183) 20160825: Euteleostomi_PTN000246452 has function vascular endothelial growth factor receptor 3 binding (GO:0043185) 20160825: Euteleostomi_PTN000246452 has function platelet-derived growth factor receptor binding (GO:0005161) 20160825: Euteleostomi_PTN000246383 has function vascular endothelial growth factor receptor 1 binding (GO:0043183) 20160825: Euteleostomi_PTN000246383 has function vascular endothelial growth factor receptor 2 binding (GO:0043184) 20160825: Euteleostomi_PTN000748769 has function vascular endothelial growth factor receptor binding (GO:0005172) 20160825: Euteleostomi_PTN000246477 has function vascular endothelial growth factor receptor 3 binding (GO:0043185) # cellular_component 20160825: node_PTN000246442 is found in extracellular space (GO:0005615) # biological_process 20160825: node_PTN000246442 participates in vascular endothelial growth factor receptor signaling pathway (GO:0048010) 20160825: node_PTN000246442 participates in angiogenesis (GO:0001525) 20160825: node_PTN000246442 participates in positive regulation of angiogenesis (GO:0045766) 20160825: node_PTN000246442 participates in positive regulation of mast cell chemotaxis (GO:0060754) 20160825: node_PTN000246442 participates in positive regulation of endothelial cell proliferation (GO:0001938) 20160825: node_PTN000246442 participates in induction of positive chemotaxis (GO:0050930) 20160825: node_PTN000246442 participates in response to hypoxia (GO:0001666) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).