# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20140724: root_PTN000234102 has function oxidoreductase activity (GO:0016491) 
20140724: node_PTN000234184 has function dihydroorotate dehydrogenase activity (GO:0004152) 
20140724: node_PTN000234103 has function dihydropyrimidine dehydrogenase (NADP+) activity (GO:0017113) 
20140724: node_PTN000234342 has function glutamate synthase activity (GO:0015930) 
20140724: Eukaryota_PTN000234268 has function NADPH-adrenodoxin reductase activity (GO:0015039) 
20140724: node_PTN000941277 has function electron carrier activity (GO:0009055) 

# cellular_component
20140724: root_PTN000234102 is found in cytoplasm (GO:0005737) 
20140724: Eukaryota_PTN000234268 is found in mitochondrion (GO:0005739) 
20140724: node_PTN000941277 is found in membrane (GO:0016020) 

# biological_process
20140724: node_PTN000234184 participates in 'de novo' pyrimidine nucleobase biosynthetic process (GO:0006207) 
20140724: node_PTN000234103 participates in uracil catabolic process (GO:0006212) 
20140724: node_PTN000234342 participates in ammonia assimilation cycle (GO:0019676) 
20140724: node_PTN000234342 participates in glutamate biosynthetic process (GO:0006537) 
20140724: node_PTN000941277 participates in anaerobic respiration (GO:0009061) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
PTN000234342
- Did not propagate glutamate synthase activity in the gltD clade because the evidence is based on a biochemical characterization paper where the protein is not clearly identified.
- Propagated glumatate biosynthetic process because it's on the same operon as other genes involved in the process.
S. cereviaise URA1
- Falls in the PTN000234103 family, but based on its activity (dihydroorotate dehydrogenase activity) activity (GO:0004152)), it looks like it belongs in the PTN000234184 family, which does not contain any cerevisiae sequence.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).