# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 07 May 2016: Updated by: TOUCHUP-v1.18 # molecular_function 20160209: root_PTN000197843 has function rRNA (adenine-N6,N6-)-dimethyltransferase activity (GO:0000179) 20160209: Ascomycota_PTN001712033 has function mitochondrial RNA polymerase core promoter sequence-specific DNA binding (GO:0000997) 20160209: Ascomycota_PTN001712033 has function mitochondrial RNA polymerase binding promoter specificity activity (GO:0034246) 20160209: Ascomycota_PTN001712033 has LOST/MODIFIED function rRNA (adenine-N6,N6-)-dimethyltransferase activity (GO:0000179) # cellular_component 20160209: root_PTN000197843 is found in cytoplasm (GO:0005737) 20160209: Eukaryota_PTN000197847 is found in mitochondrial matrix (GO:0005759) 20160209: Ascomycota_PTN001712033 is found in mitochondrial DNA-directed RNA polymerase complex (GO:0034245) 20160209: Magnoliophyta_PTN000197901 is found in mitochondrion (GO:0005739) 20160209: node_PTN001712109 is found in mitochondrial matrix (GO:0005759) # biological_process 20160209: Eumetazoa_PTN000919642 participates in transcription from mitochondrial promoter (GO:0006390) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).